部份中文格列吡脲处方资料（仅供参考）
英文名：Glyclopyramide
商品名：DEAMELIN S Tablets
中文名：格列吡脲片
生产商：杏林药业
デアメリンS錠250mg
药品分类名
口服降糖药
批准日期：2007年12月
欧文商標名
DEAMELIN・S Tablets 250mg
一般名：グリクロピラミド(Glyclopyramide)[JAN]
化学名：N-(p-Chlorobenzenesulfonyl)-N´-pyrrolidinourea
分子式：C11H14ClN3O3S
分子量：303.77
融　点：195〜200℃
性　状：
该产品为白色结晶粉末，无臭。 该产物微溶于二甲基甲酰胺，微溶于丙酮或氯仿，几乎不溶于水，乙醇（95）或乙醚。 该产物可溶于氢氧化钠试剂或氨试剂。
分配系数：
见分配系数表
化学结构式：
有关有效成分的理化检查结果表
分配系数

（25°C）
药效与药理
对兔口服给予150mg/kg的吡咯酰胺的结果是，药物血药浓度与低血糖峰一致，均在1小时后出现。 另外，在对大鼠给予吡咯乙酰胺1小时后的剂量响应（12.5至100mg/kg）中观察到线性，并且降血糖效果是甲苯磺丁酰胺的2.66倍。
适应症
非胰岛素依赖型糖尿病（前提是饮食和运动效果不佳）
用法与用量
通常，每天口服125至250mg的吡咯酰胺，并适当增加剂量以确定维持剂量。但是，最大每日剂量为500毫克。
至于给药方法，对于单次给药，在早餐之前或之后口服给药，对于双次给药，在早餐或晚上之前或之后口服给药。
包装
S片
250mg
PTP包装：100片（10片x 10），500片（10片x 50）
制造业销售（进口）来源
杏林制药有限公司
注：以上中文处方资料不够完整，使用者以原处方资料为准。
完整说明资料附件：
https://www.info.pmda.go.jp/go/pack/3961002F1031_1_10/?view=frame&style=SGML&lang=ja
DEAMELIN†S Tablets 250mg（Glyclopyramide，デアメリンS錠250mg）
Brand name : DEAMELIN†S Tablets 250mg
　Active ingredient: Glyclopyramide
　Dosage form: white tablet (major axis: 13.0mm, minor axis: 5.5 mm, thickness: 4.2 mm)
　Print on wrapping: face: デアメリンS錠250mg, KP-105, back: DEAMELIN･S Tab.250mg, デアメリンS錠250mg
Effects of this medicine
This medicine acts on the pancreas to stimulate insulin secretion, and consequently lowers blood glucose.
It is usually used in the treatment of insulin-independent diabetes mellitus.
Before using this medicine, be sure to tell your doctor and pharmacist
If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you are a patient with ketosis, diabetic coma or precoma, insulin-dependent diabetes mellitus, hepatic or renal disorder, infections, an injury, diarrhea, or gastrointestinal disorder.
If you are before or after undergoing a surgery.
If you are pregnant or breastfeeding.
If you are taking any other medicinal products.(Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines)
Dosing schedule (How to take this medicine)
Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
General dosage regimen: For adults, take a half to one tablet(125-250mg of the active ingredient) daily. The dosage may be increased as necessary and the maintenance dose will be determined. However, the maximum daily dose is limited to 2 tablets (500 mg). If you instructed to take the medicine once daily, take it before or after breakfast, or twice daily, before or after breakfast and supper. Strictly follow the instructions of your doctor/pharmacist.
Skip the missed dose and continue your regular dosing schedule. DO NOT take double doses to make up for the missed dose.
If you took too much of the medicine(more than ordered), check with your doctor/pharmacist.
Do not stop taking the medicine without the instructions of your doctor.
Precautions while taking this medicine
Strictly follow diet and exercise therapy instructed by your doctor.
The medicine may cause hypoglycemia. Pay close attention to avoid any accident when you work at heights, drive a car or operate dangerous machinery after taking the medicine.
If you noticed any symptoms of hypoglycemia(sweating, hungry feeling, shaky limbs, etc.), take sugar or juice including glucose and consult with your doctor. To take a measure for these symptoms, carry sugar with you.
Tell your family members that you take the medicine in case that impairment of consciousness (one of the symptoms of hypoglycemia) occurs.
Possible adverse reactions to this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: hypoglycemia, loss of appetite, abdominal discomfort, etc.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
sweating, hungry feeling, shaky limbs[hypoglycemia]
symptom of anemia, bleeding tendency, sore throat[aplastic anemia, agranulocytosis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
Keep the medicine out of the reach of children. Store it away from direct sunlight, heat and moisture.
Do not store the remainder and ask your pharmacist how to discard it.
Kyorin Pharmacetical Co.,Ltd Internal
Published: 7/2008
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits).It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.