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The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
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Brand name :
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CAPTORIL-R CAPSULES 18.75mg
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Dosage form:
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white capsule with reddish brown belt, major axis : 15.8 mm, minor axis : 5.8 mm
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Print on wrapping:
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(front) カプトリル-Rカプセル18.75mg, 第一三共エスファ, カプトリル-R, 18.75mg, 271, (back) CAPTORIL-R 18.75mg, 血圧降下薬, カプトリル-R, 18.75mg
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Effects of this medicine
This medicine inhibits angiotensin-converting enzyme to suppress production of angiotensin II, and consequently shows antihypertensive action by dilating peripheral blood vessels and decreasing vascular resistance. It also suppresses secretion of aldosterone to show sodium excretory effect.
It is usually used in the treatment of essential hypertension and renal hypertension.
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Before using this medicine, be sure to tell your doctor and pharmacist
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If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have a history with angioedema.
If you are receiving apheresis or hemodialysis.
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If you are pregnant, possibly pregnant or breastfeeding.
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If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
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Dosing schedule (How to take this medicine)
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Your dosing schedule prescribed by your doctor is << to be written by a healthcare professional>>
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In general, for adults, take 1 to 2 capsules (18.75 to 37.5 mg of the active ingredient) at a time, twice daily. The dosage may be adjusted according to the diseases, age or symptoms. In the treatment of severe essential hypertension and renal hypertension, it is desirable to start taking 1 capsule (18.75 mg) at a time, once or twice daily. Strictly follow the instructions.
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If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
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If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
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Do not stop taking this medicine unless your doctor instructs you to do so.
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Precautions while taking this medicine
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Dizziness and lightheadedness may occur due to decreased blood pressure. Pay attention to performing dangerous operations such as driving a car or working at heights.
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Possible adverse reactions to this medicine
The most commonly reported adverse reactions include cough, rash, itch, hives, photosensitivity, anemia, taste abnormality and jaundice. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
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respiratory distress; swelling in the face, tongue, glottis or larynx; hives [angioedema]
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general malaise, headache, throat pain, gum bleeding, subcutaneous bleeding [pancytopenia, agranulocytosis]
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decreased urine output, edema, loss of appetite [acute renal failure, nephrotic syndrome]
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numbness in the limbs and lips, muscular weakness, paralysis in the limbs [hyperkalemia]
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blisters appearing on the skin, severe itchiness throughout the body [pemphigus like symptoms]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
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Storage conditions and other information
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Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
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Discard the remainder. Do not store them.
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