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REBETOL capsules 200mg(レベトールカプセル200mg)
2016-05-24 04:34:52 来源: 作者: 【 】 浏览:415次 评论:0

Internal
Revised: 7/2015

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
REBETOL capsules 200mg
 Active ingredient:
Ribavirin
 Dosage form:
white opaque hard gelatin capsule (length: 19.2mm)
 Print on wrapping:
(Face) 921 (Back)レベトール, 200mg, 921

Effects of this medicine

This medicine is used with interferon preparations (interferon alpha-2b, peginterferon alpha-2b or interferon beta) and other antiviral agents to inhibit the growth of hepatitis C virus. It also helps eliminating the virus from your body so that to improve the liver functioning.
It is usually used to treat chronic hepatitis C.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have heart disease (myocardial infarction, heart failure, arrhythmia), abnormal hemoglobin disease (thalassemia, drepanocytic anemia), kidney/liver disorder, autoimmune hepatitis, mental illness or with history of it.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is <<        to be written by a healthcare professional>>
  • In general, for adults, take this medicine according to your body weight after meals. If your weight is 60kg and below, take 3 capsules (600 mg) a day [1capsule (200 mg) after breakfast and 2 capsules (400 mg) after dinner]. If your weight ranges over 60kg to 80kg, take 4 capsules (800 mg) a day [2 capsules (400 mg) after breakfast and 2 capsules (400 mg) after dinner]. If your weight is over 80kg, take 5 capsules (1,000 mg) a day [2 capsules (400 mg) after breakfast and 3 capsules (600 mg) after dinner]. The dosage should be reduced or this medicine should be discontinued according to your age and symptoms. Strictly follow the instructions.
  • If you miss a dose, consult with your doctor or pharmacist. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking the medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Female patient who may possibly become pregnant must have a pregnancy test each month during the medication and for 6 months afterward in order to make sure you are not pregnant. And if you/your partner can possibly become pregnant, you/your partner should avoid pregnancy and should use a reliable contraceptive method while you are taking the medicine and for 6 months after the treatment.
  • Male patients: If your partner is pregnant or possibly become pregnant, wear condoms during the medication and for 6 months afterward in order to prevent transporting semen into the uterus.
  • Follow your doctor's instructions and take periodical blood tests.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include fever, lassitude, headache, top-heavy feeling, chills, sleeplessness, loss of appetite, vomiting, nausea, joint pain, muscle pain, abdominal pain, anaemia, eye floater (view of flying mosquito), visual degradation and itch. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • palpitation when going upstairs or uphill, shortness of breath, dizziness [anemia]
  • sore throat, muscle pain, high fever with chills or shivering [blood disorders such as agranulocytosis and leukopenia]
  • sleeplessness, anxiety, irritation [depression, suicide attempt, manic state, aggressive behavior]
  • facial pallor, cold sweat, dizziness on standing up [shock]
  • dry cough, breathing difficulty, general malaise, fever [interstitial pneumonia, pulmonary fibrosis, pulmonary edema]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store at room temperature (1 to 30℃), away from direct sunlight and moisture.
  •  Discard the remainder. Do not store them. Ask the pharmacy or medical institution how to discard.
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