近期一项Ⅱ期试验使用高低两种剂量的硝唑尼特控释片剂，显示其良好的药代动力学，使病毒载量显著降低，并有良好的耐受性和安全性。

硝唑尼特说明书

ALINIA

 Alinia InformationAlinia is a medical product that is also well known as Nitazoxanide. This medication belongs to a wide class of drugs - antiprotozoals. Such products are widely prescribed in the therapy of diarrhea that has been triggered by a certain form of protozoa.

 Alinia IndicationsAlinia is quite effective in the prophylaxis for diarrhea in the case of children and adults, if the symptom is caused by Giardia lamblia or other types of protozoa (including Cryptosporidium parvum). In other words, a therapy with this medicine is prescribed to patients who are diagnosed with travelers' diarrhea. However, a treatment trial with this medicine can prove effective in the therapy of some other medical conditions. It is important to refer to your personal health care provider if you have any further questions regarding this matter.

 Alinia WarningsThe presence of other medical disorders (apart from traveler’s diarrhea) can prevent an individual from being prescribed a treatment trial with Alinia. For this reason, it is important to alert your personal health care provider if you are suffering from any immune system medical conditions (including HIV), kidney disorders or any liver medical conditions. While some patients who present these medical disorders will not be allowed to start using Alinia on a regular basis, others will be prescribed lower doses of this drug. However, their therapy with this antiprotozoal must be closely supervised by an authorized health care provider.

 The oral form (suspension) of Alinia is known to contain about 1.48 grams of sucrose in a teaspoon of medicine (5 mL). This is why patients who are suffering from diabetes should lower their daily intake of sucrose during their therapy with this type of medicine.

 Studies have shown that Nitazoxanide (Alinia) is a category B FDA pregnancy medicine. In other words, a treatment trial with this medical product should not harm a growing fetus in any way. However, it is best that each pregnant female who wants to start using this medicine on a regular basis should discuss the prospects of a potential therapy with Alinia with her personal health care provider. It has not yet been determined whether the ingredients of this medication are able to pass into the patient’s breast milk or not. In such conditions, we recommend all nursing mothers to stop breastfeeding their infants during their treatment trial with this medical product.

 Alinia Intake GuidelinesYour personal health care provider is entitled to prescribe you the necessary precautions that you ought to take into consideration during your future therapy with Alinia. He or she will also tell you exactly how you should use each of your doses of this medical product.