设为首页 加入收藏

TOP

Glycerol Injection 10bag×500ml(グリセオール注.甘油果糖氯化钠输液)
药店国别  
产地国家 日本 
处 方 药: 是 
所属类别 500毫升/袋 100袋/箱 
包装规格 500毫升/袋 100袋/箱 
计价单位: 箱 
生产厂家中文参考译名:
中外制药
生产厂家英文名:
Chugai Pharmaceutical Co.
该药品相关信息网址1:
http://www.info.pmda.go.jp/go/pack/2190501A4084_2_02/
该药品相关信息网址2:
该药品相关信息网址3:
原产地英文商品名:
GLYCEOL(グリセオール注)500ML/bag 10bag/CASE
原产地英文药品名:
Sodium Chloride Fructose Concentrated glycerin
中文参考商品译名:
GLYCEOL(グリセオール注)500毫升/袋 10袋/箱
中文参考药品译名:
甘油果糖浓氯化钠
曾用名:
简介:

 

部分中文甘油果糖氯化钠处方资料(仅供参考)
英文名:Glycerin/Fructose/Sodium Chloride
商品名:Glycerol Injection
中文名:甘油果糖氯化钠输液
生产商:中外制药
药品简介
Glycerol(甘油果糖氯化钠)是一种高渗性脱水药物,临床主要用于颅内压升高,脑水肿,脑血栓,脑内出血等脑病及用于降低脑内压和眼手术时的眼容积缩小等。
グリセオール注/グリセオール注/グリセオール注
药效分类
头盖内压亢进・头盖内浮肿治疗剂
眼压降落剂
批准日期:2004年7月
商標名
GLYCEOL
使用上注意
1.注射针要直刺橡胶栓上的○符号。斜刺的话注射针贯穿容器颈部,成为液漏的原因。
2.因为不能使用联结管(U字管)的串联方式来使用,所以在同时或连续使用2包的情况下,使用Y型输液组套。
3.不要使用包装内有水滴、内容液着色或混浊物。
4.容器的液体刻度要作为大概的标准来使用。
药理学
1.给猫和兔子静脉注射glycerin后,发现它们都有明显的脑脊髓液压下降作用。
2.将本药给兔子静脉注射后,发现前房内压及玻璃体内压的下降作用。
3.根据狗硬膜外baloon法及cold-injury法制作的脑障碍模型在静脉内服用本药后,以增加的脑水分量的减少为首,脑血流量增加、脑氧消耗量增加、脑组织代谢改善等作用。
4.将本药给猫实验性脑虚血模型静脉注射,经生理学和组织学研究发现,对脑虚血性障碍起到保护作用。
5.对人(需要头盖内压或眼内压下降的患者)静脉注射本剂的结果,本剂迅速地表示了强的头盖内压下降作用,眼内压下降作用。
6.给(脑中风)注入本剂或glycerin,测定局部脑循环后,发现从虚血状态到正常状态的血流增加作用,也承认了从充血部位到虚血部位的血流再分配作用。
7.对人(脑中风)使用glycerin时,脑浮肿形成的恶性循环因子即脑细胞内被认为是能量产生障碍因子的游离脂肪酸的减少等与脑代谢有关的事被认可了。
适应症
头盖内压亢进、头盖内浮肿的治疗
由于头盖内压亢进,头盖内浮肿的改善伴随下列疾病的意识障碍,神经障碍,自觉症状的改善
脑梗塞(脑血栓、脑堵塞)、脑内出血、蜘蛛膜下出血、头部外伤、脑肿瘤、脑髓膜炎
脑外科手术后的后疗法
脑外科手术时的脑容积缩小
眼科手术时的眼容积缩小
用法与用量
通常,成人1次200~500mL1日1~2次,500mL每2~3小时挂上(放上)点滴静注。
服用期通常为1~2周。
再者,根据年龄,症状适当地增减。
脑外科手术时的脑容积缩小的目的,一次用30分钟点滴静注500mL。
眼内压降及眼科手术时的眼容积缩小的目的是,一次用45~90分钟静脉注射300~500mL。
临床成绩
1.以头盖内压亢进、脑浮肿状态持续的患者(61症例)为对象的双重盲检比较试验中,将本剂500mL花费2小时在静脉内给病人服用后,能迅速降低头盖内压、减轻脑浮肿、改善脑血流等效果,还能改善自・他觉观察,有用性明确了。
综合整体改善度(第三者判定)〔改善以上〕:41.4%。
2.对伴随脑浮肿及头盖内压亢进的各种中枢神经疾病患者(17设施253例)1日从500mL向1000mL静脉内注射本剂的结果,脑脊髓液压有意下降,被认为是头盖内压亢进症状的自・他觉症状改善到61.7%。
3.在以绿内障患者及白内障或绿内障术前处理患者(57病例)为对象的双重盲检比较试验中,以60~90分钟的使用速度给本剂500mL服用静脉,结果被认定有用性。
有用率〔有用以上〕:87.7%
包装
*200mL:10袋(10袋×1)(バッグ)、20袋(5袋×4)(バッグ)
*300mL:10袋(10袋×1)(バッグ)、20袋(5袋×4)(バッグ)
*500mL:10袋(10袋×1)(バッグ)、20袋(5袋×4)(バッグ)
注:以上中文处方资料不够完整,使用者以原处方资料为准。
完整说明附件:
http://www.info.pmda.go.jp/go/pack/2190501A4084_3_01/
------------------------------------------------------------------------
GLYCEOL Injection 500mL(グリセオール注[500mL]) 
Brand name : GLYCEOL Injection 500mL
 Active ingredient: Concentrated glycerin
 Fructose
 Dosage form: injection
 Print on wrapping: 
Effects of this medicine
This medicine reduces swelling of the brain (brain edema) and lowers brain pressure (intracranial pressure). This medicine also has an action to lower intraocular pressure.
It is usually used for intracranial pressure lowering, improvement of intracranial pressure edema, postoperative therapy following brain surgery, intraocular pressure lowering and brain/eye surgery.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have congenital glycerin/fructose metabolic disorders, adult-onset type II citrullinemia, cardiac disorder, or circulation organs dysfunction.
If you have renal disorder, diabetes insipidus, diabetes mellitus or intake restriction of salt.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•For intracranial pressure lowering, improvement of intracranial pressure edema, and postoperative therapy following brain surgery: In general, for an adult, inject with intravenous drip infusion once or twice a day.
•For brain surgery: In general, inject with intravenous drip infusion over a 30-minute period.
•For intraocular pressure lowering and eye surgery: In general, inject with intravenous drip infusion over a 45-90 minute period.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include hemoglobinuria, hematuria, micturition, headahce and dry mouth. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
•nausea, vomiting, abdominal pain, breathlessness, hyperventilation, feeling of weariness, tremor, loss of consciousness  [acidosis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
Chugai Pharmaceutical Co., Ltd.Injection
Revised: 8/2012
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.  

】【打印繁体】【投稿】【收藏】 【推荐】【举报】【评论】 【关闭】 【返回顶部
分享到QQ空间
分享到: 
上一篇Glycerol Injection 20bag×500ml.. 下一篇Glycerol Injection 20bag×300ml..

相关栏目

最新文章

图片主题

热门文章

推荐文章