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Xarelto [拜瑞妥]

2015-02-09 09:07:43 来源: 作者: 【大中小】浏览:1915次评论:0条

See related Xarelto film-coated tab[拜瑞妥膜衣錠] information

製造商	Bayer Schering Pharma
代理/經銷商	Bayer Schering Pharma
成份	Rivaroxaban
適應症	Prevention of VTE in adult patients undergoing elective hip or knee replacement surgery.
用量	10 mg once daily. Initial dose should be taken 6-10 hr after surgery. Duration of treatment: Major hip surgery 5 weeks. Major knee surgery 2 weeks.
禁忌	Clinically significant active bleeding. Hepatic disease associated with coagulopathy & clinically relevant bleeding risk. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Children & adolescent < 18 years. Pregnancy & lactation. Renal impairment with CrCl < 30 mL/min.
注意事項	Haemorrhagic risk, congenital or acquired bleeding disorders, uncontrolled severe arterial HTN, active & recent GI ulcerations, vascular retinopathy, recent intracranial or intracerebral hemorrhage, intraspinal or intracerebral vascular abnormalities. Recent brain, spinal or ophthalmological surgery, hip fracture surgery, spinal/epidural anesth or puncture. Renal & hepatic impairment.
不良反應	Increased GGT, increase in transaminases (ALT & AST); anemia; nausea; post-op hemorrhage. View ADR Monitoring Website[參閱藥物不良反應監測表格]
交互作用	Azole antimycotics (e.g. ketoconazole, itraconazole, voriconazole, posaconazole, fluconazole), HIV protease inhibitors, CYP3A4 inducers ( e.g. rifampicin, phenytoin, carbamazepine, phenobarbital or St John's wort). View more drug interactions with Xarelto[拜瑞妥]