See related Ixempra inj[易莎平 注射劑] information |
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製造商 |
Bristol-Myers Squibb |
代理/經銷商 |
Bristol-Myers Squibb |
成份 |
Ixabepilone |
適應症 |
In combination with capecitabine for the treatment of metastatic or locally advanced breast cancer in patients after failure of an anthracycline & a taxane. |
用量 |
40 mg/m2 IV over 3 hr every 3 weeks. |
過量 |
View Ixempra[易莎平] overdosage for action to be taken in the event of an overdose. |
美國食品藥物管理局之懷孕等級 |
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). |
禁忌 |
Severe hypersensitivity to polyoxyethylated castor oil-containing agents. Patients who have a neutrophil count <1500 cells/mm3 or platelet count <100,000 cells/mm3, AST or ALT >2.5 x ULN or bilirubin >1 x ULN. |
注意事項 |
Monitor for symptoms of neuropathy. Severe neutropenia or thrombocytopenia; hepatic impairment, cardiac disorders. Pregnancy & lactation. Children. May impair ability to drive or operate machinery. |
不良反應 |
Peripheral sensory neuropathy, fatigue/asthenia, myalgia/arthralgia, alopecia, nausea, vomiting, stomatitis/mucositis, diarrhea & musculoskeletal pain. Combination therapy: Palmar-plantar erythrodysesthesia syndrome, anorexia, abdominal pain, nail disorder & constipation.
View ADR Monitoring Website[參閱藥物不良反應監測表格] |
交互作用 |
Ketoconazole, itraconazole, ritonavir, amprenavir, rifampicin, rifabutin, indinavir, nelfinavir, delavirdine, voriconazole; erythromycin,fluconazole,verapamil; dexamethasone, phenytoin, carbamazepine, rifampin, phenobarb; St. John's wort; grapefruit juice.
View more drug interactions with Ixempra[易莎平] |
使用上注意 |
For caution against possible variation of physical aspect of medicine... click to view Ixempra[易莎平] detailed prescribing infomation |
儲存 |
View Ixempra[易莎平] storage conditions for details to ensure optimal shelf-life. |
描述 |
View Ixempra[易莎平] description for details of the chemical structure and excipients (inactive components). |
作用 |
View Ixempra[易莎平] mechanism of action for pharmacodynamics and pharmacokinetics details. |
本商品之市售規格 |
劑型 |
包裝 |
圖片 |
Ixempra 注射劑 |
Ixempra 15 mg |
Ixempra 45 mg |
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Manufacturer: |
Bristol-Myers Squibb |
Distributor: |
Bristol-Myers Squibb
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