健保碼及健保價 
See related Leukeran tab[瘤克寧 錠] information 
 
製造商 GlaxoSmithKline 
代理/經銷商 GlaxoSmithKline 
成份 Chlorambucil
適應症 Listed in Dosage.
用量 Hodgkin's disease Monotherapy: 0.2 mg/kg/day for 4-8 week. Non-Hodgkin's lymphoma Monotherapy: 0.1-0.2 mg/kg/day for 4-8 week initially. Maintenance therapy is given by reduced daily dosage or intermitten courses of treatment. Chronic lymphocytic leukaemia 0.15 mg/kg/day until the total leucocyte count has fallen to 10,000/microlitre. Treatment may be resumed 4 week after the end of the 1st course & continued at 0.1 mg/kg/day. Waldenstrom's macroglobulinaemia Starting dose: 6-12 mg daily until leucopenia occurs; followed by 2-8 mg daily indefinitely.
過量 View Leukeran[瘤克寧] overdosage for action to be taken in the event of an overdose.
用法 Should be taken on an empty stomach (Take on an empty stomach. Ensure adequate hydration. Swallow whole, do not chew/crush.).
美國食品藥物管理局之懷孕等級      
     
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). 
禁忌 Pregnancy (1st trimester) & lactation.
注意事項 Immunization with live vaccines. Monitor blood counts closely. Recently undergone radio- or chemotherapy. In lymphocytic infiltration of bone marrow or hypoplastic bone marrow, max daily dose is 0.1 mg/kg. Monitor closely children with nephrotic syndrome, patients on high intermitten dosing regimens, history of seizure disorders. Renal/hepatic impairment. Mutagenicity & carcinogenicity (chromatid or chromosome damage). Acute myelogenous leukemia with long-term adjuvant therapy for breast cancer.
不良反應 Acute secondary hematologic malignancies (especially leukemia & myelodysplastic syndrome), particularly after long-term treatment. Leucopenia, neutropenia, thrombocytopenia, pancytopenia. Bone marrow suppression; anemia, seizures in children with nephrotic syndrome; nausea, vomiting, diarrhea, oral ulceration.
View ADR Monitoring Website[參閱藥物不良反應監測表格]
交互作用 Phenylbutazone, live vaccines.
View more drug interactions with Leukeran[瘤克寧]
儲存 View Leukeran[瘤克寧] storage conditions for details to ensure optimal shelf-life.

本商品之市售規格
劑型 包裝 圖片
Leukeran 錠劑  Leukeran 2 mg x 25's 
 
 
Manufacturer: GlaxoSmithKline
 
Distributor: GlaxoSmithKline