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健保碼及健保價 |
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See related Cosmegen powd for inj[可美淨 乾粉注射劑] information |
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製造商 |
Invida |
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代理/經銷商 |
Excelsior |
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成份 |
Dactinomycin |
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適應症 |
Treatment of cancers in children & testicular cancer. Wilms' tumor, rhabdomyosarcoma, palliative treatment of other types of cancer. |
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用量 |
Adult 0.5 mg IV daily for max. 5 days. Children 15 mcg/kg IV for 5 days or total dosage of 2,500 mcg/m2 IV for 7 days. Adult & children 2nd cycle can only start 3 weeks later. |
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過量 |
View Cosmegen[可美淨] overdosage for action to be taken in the event of an overdose. |
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美國食品藥物管理局之懷孕等級 |
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). |
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禁忌 |
Chicken pox or herpes zoster infections. Pregnancy, lactation. |
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注意事項 |
Toxic & extremely corrosive to soft tissue. Inhalation of dust or vapours & contact with skin or mucous membranes, especially those of the eyes must be avoided. Veno-occlusive disease (primarily hepatic) may result in fatality, particularly in children < 48 months. Increased incidence of GI toxicity, marrow suppression, erythema reported in combination with radiation. Caution is necessary when administering within 2 months of irradiation for the treatment of right-sided Wilms' tumour. Should not be concomitantly administered with radiotherapy in the treatment of Wilms' tumour unless the benefit outweighs the risk. Frequent monitoring of renal, hepatic & bone marrow function. Infants < 6-12 months. |
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不良反應 |
Malaise, fatigue, lethargy, fever, myalgia, proctitis, hypocalcemia, growth retardation, infection. Pneumonitis. Cheilitis, dysphagia, esophagitis, ulcerative stomatitis, pharyngitis. Anorexia, nausea, vomiting, abdominal pain, diarrhea, gastrointestinal ulceration. Liver toxicity including liver function test abnormalities, ascites, hepatomegaly, hepatitis, hepatic failure with reports of death, hepatic veno-occlusive disease which may be associated with intravascular clotting disorder & multi-organ failure. Anemia, agranulocytosis, leukopenia, neutropenia, febrile neutropenia, thrombocytopenia. Baldness, skin eruptions, acne, flare-up of erythema or darkening pigmentation of skin.
View ADR Monitoring Website[參閱藥物不良反應監測表格] |
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副作用 |
View Cosmegen[可美淨] side effects |
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交互作用 |
Live virus vaccines.
View more drug interactions with Cosmegen[可美淨] |
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使用上注意 |
For caution against possible variation of physical aspect of medicine... click to view Cosmegen[可美淨] detailed prescribing infomation |
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儲存 |
View Cosmegen[可美淨] storage conditions for details to ensure optimal shelf-life. |
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作用 |
View Cosmegen[可美淨] mechanism of action for pharmacodynamics and pharmacokinetics details. |
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本商品之市售規格 |
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劑型 |
包裝 |
圖片 |
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Cosmegen 乾粉注射劑 |
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Cosmegen 0.5 mg x 1's |
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Manufacturer: |
Invida |
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Distributor: |
Excelsior |
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