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See related Actonel film-coated tab information |
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Manufacturer |
sanofi-aventis |
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Distributor |
DKSH |
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Contents |
Risedronate Na |
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Indications |
Treatment of established postmenopausal osteoporosis. Treatment of osteoporosis in men at high risk of fractures. Prevention of osteoporosis in postmenopausal women w/ increased risk of osteoporosis. Prevention & treatment of glucocorticoid-induced osteoporosis in men & women who are either initiating or continuing systemic glucocorticoid treatment (daily dosage equiv to ≥7.5 mg of prednisone) for chronic diseases.
Click to view Actonel detailed prescribing infomation |
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Dosage |
Treatment & prevention of postmenopausal osteoporosis One 35-mg tab once wkly or one 5-mg tab once daily. Treatment of osteoporosis in men One 35-mg tab once wkly or one 5-mg tab once daily. Treatment & prevention of glucocorticoid-induced osteoporosis in men & women 5-mg tab once a day.
Click to view Actonel detailed prescribing infomation |
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Overdosage |
View Actonel overdosage for action to be taken in the event of an overdose. |
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Administration |
Should be taken on an empty stomach (5-mg tab to be taken at least 30 min before the 1st food/drink/medication of the day; or at least 2 hr from any food/drink at any other time of the day, & at least 30 min before going to bed. 35-mg tab to be taken at least 30 min before the 1st food/drink/medication of the day. To be taken on the same day each week. 5-mg & 35-mg tab: Take w/ a full glass (180-240 mL) of plain water while in an upright position. Do not lie down for at least 30 min after taking. Swallow whole, do not chew/crush/suck.). |
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Contraindications |
Hypocalcaemia, pregnancy & lactation, severe renal impairment (CrCl <30 mL/min).
Click to view Actonel detailed prescribing infomation |
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Warnings |
For additional cautionary notes to warn of the potential risk of using the medicine... click to view Actonel detailed prescribing infomation |
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Special Precautions |
History of oesophageal disorders which delay oesophageal transit or emptying, inability to remain in an upright position for at least 30 min after tablet intake; correct hypocalcaemia & treat other disturbances of bone & mineral metabolism before initiating therapy.
Click to view Actonel detailed prescribing infomation |
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Adverse Drug Reactions |
Bone pain, muscle & joint pain & stomachache. Uncommon: Duodenitis, glossitis, iritis.
View ADR Monitoring Form |
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Drug Interactions |
Multivalent cations (eg Ca, Mg, Fe, Al) may interfere w/ absorption of Actonel.
View more drug interactions with Actonel |
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Pregnancy Category (US FDA) |
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus. |
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Storage |
View Actonel storage conditions for details to ensure optimal shelf-life. |
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Description |
View Actonel description for details of the chemical structure and excipients (inactive components). |
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Mechanism of Action |
View Actonel mechanism of action for pharmacodynamics and pharmacokinetics details. |
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