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Manufacturer Pfizer 
Distributor Zuellig 
Contents Methylprednisolone Na succinate
Indications Endocrine, rheumatic & hematologic disorders; collagen, dermatologic, ophth, GI, resp & neoplastic disease; allergic & edematous states; acute exacerbation of multiple sclerosis; tuberculous meningitis w/ subarachnoid or impending block; Trichinosis w/ neurologic or myocardial involvement; cerebral edema from tumors; acute spinal cord injury (treatment should begin w/in 8 hr of injury).
Dosage Adjunct in life-threatening conditions 30 mg/kg over 30 min, may be repeated 4-6 hrly for up to 48 hr. Rheumatic disorders 1 g/day for 1-4 days, IV pulse dosing over at least 30 min, may be repeated if improvement has not occurred w/in a wk. SLE 1 g/day for 3 days. Multiple sclerosis 1 g/day for 3-5 days. Acute spinal cord injury 30 mg/kg as an IV bolus over 15 min followed by a 45-min pause, then continuous IV infusion of 5.4 mg/kg/hr for 23-47 hr. Childn & infant Min dose: 0.5 mg/kg 24 hrly.
Contraindications Premature infants. Systemic fungal infections.
Special Precautions Hypothyroidism, cirrhosis. Ocular herpes simplex. Psychotic tendencies. Nonspecific ulcerative colitis, a probability of impending perforation, abscess or other pyogenic infection; diverticulitis; fresh intestinal anastomoses; active or latent peptic ulcer; renal insufficiency; HTN; osteoporosis; myasthenia gravis. Infants & childn.
Adverse Drug Reactions Fluid & electrolyte imbalance; musculoskeletal effects; peptic ulcer w/ perforation & hemorrhage; pancreatitis; abdominal distension; ulcerative esophagitis; increases in liver enzymes; dermatologic reactions; increased intracranial pressure w/ papilledema (pseudotumor cerebri); Cushingoid state; suppression of growth in childn; secondary adrenocortical & pituitary unresponsiveness, menstrual irregularities; decreased carbohydrate tolerance; manifestations of latent DM; ophth disorders; negative nitrogen balance due to protein catabolism.
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Drug Interactions Cyclosporine, phenobarb, phenytoin, rifampin, troleandomycin, ketoconazole, aspirin, anticoagulants.
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Pregnancy Category (US FDA)      
     
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus. 

Presentation/Packing
Form Packing Photo
Solu-Medrol infusion  Solu-Medrol 2 g x 1's
Solu-Medrol 500 mg x 1's
Solu-Medrol 1000 mg x 1's
 
Solu-Medrol Vial  Solu-Medrol 40 mg x 1's
Solu-Medrol 125 mg x 1's
 
Manufacturer: Pfizer
 
Distributor: Zuellig