Drug Class Description
Antiviral/Protease Inhibitor
Generic Name
Fosamprenavir
Drug Description
Each ml of oral suspension contains 50 mg fosamprenavir as fosamprenavir calcium (equivalent to approximately 43 mg amprenavir).
Presentation
Oral suspension.The suspension is white to off-white in colour
Indications
Telzir in combination with low dose ritonavir is indicated for the treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infected adults, adolescents and children of 6 years and above in combination with other antiretroviral medicinal products.In moderately antiretroviral experienced adults, Telzir in combination with low dose ritonavir has not been shown to be as effective as lopinavir / ritonavir. No comparative studies have been undertaken in children or adolescents.In heavily pretreated patients the use of Telzir in combination with low dose ritonavir has not been sufficiently studied.In protease inhibitor (PI) experienced patients, the choice of Telzir should be based on individual viral resistance testing and treatment history
Adult Dosage
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Telzir must only be given with low dose ritonavir as a pharmacokinetic enhancer of amprenavir and in combination with other antiretroviral medicinal products. The Summary of Product Characteristics of ritonavir must therefore be consulted prior to initiation of therapy with Telzir. |
Therapy should be initiated by a physician experienced in the management of HIV infection.
Telzir (fosamprenavir) is a pro-drug of amprenavir and must not be administered concomitantly with other medicinal products containing amprenavir.
The importance of complying with the full recommended dosing regimen should be stressed to all patients.
Caution is advised if the recommended dose of fosamprenavir with ritonavir detailed below are exceeded.
Telzir suspension is administered orally.
Shake the bottle vigorously for 20 seconds before first dose is removed and 5 seconds before each subsequent dose.
Telzir is also available as 700 mg film-coated tablets.
Adults
