Drug Class Description
Immunosuppressants (interleukin-2 receptor antagonists).

Generic Name
Daclizumab

Drug Description
Concentrate in vial for solution for infusion.

Presentation
Infusion, daclizumab 5mg /mL.

Indications
Prophylaxis of acute organ rejection in de novo allogeneic renal transplants in conjunction with an immunosuppressive regimen.

Adult Dosage
1mg/kg by intravenous infusion over 15 minutes starting within 24 hours before transplantation. Repeat four times daily at 14 day intervals.

Child Dosage
As for adults.

Contra Indications
Pregnancy and lactation.

Special Precautions
Cardiopulmonary resuscitation equipment must be available.

Adverse Reactions
Similar to placebo.

Manufacturer
Roche

Drug Availability
(POM)