部份中文奥拉西坦处方资料(仅供参考)
【中文品名】奥拉西坦
【药效类别】脑代谢改善药>吡拉西坦类
【通用药名】OXIRACETAM
【别 名】脑复智,奥拉酰胺,4-羟基脑复康, Hydroxypiracetam,Neuromet,Neuracitym,ISF-2522,CT-848
【化学名称】 l-Pyrrolidineacetamide, 4-hydroxy-2-oxo-
【CA登记号】[62613-82-5]
【结 构 式】
【分 子 式】C6H10N2O3
【分 子 量】158.16
【收录药典】
【开发单位】ISF(意大利)
【首次上市】1984,意大利
【性 状】白色结晶性粉末。mp165~168℃。
【用 途】智能促进药。可促进磷酰胆碱、磷酰乙醇胺合成和脑代谢,老龄者长期使用,可明显改善组织机能,还可提高有脑血管损伤的老年人的学习效率。用于治疗老年性脑机能不全性精神综合征及精神行为紊乱和老年性痴呆症。
首次由意大利史克比切姆公司于1974年合成 ,1987年上市。国外上市剂型有片剂、胶囊剂、散剂、口服液、注射剂等。
OXIRACETAM (Neuromet®)
Neuromet 800 Bustine
Chemical
Oxiracetam (4-hydroxy-2-oxo-1-pyrrolidone-acetamide).
Neuromet acts upon the central nervous system, selectively activating the integrative cortical functions. Original experimentation research has shown that Oxiracetam restores the complex activity of the cerebral cortex in the presence of acute cerebral insults and of damage in the evolutionary phase. Neuromet acts positively on the cerebral metabolism increasing the receptiveness of ATP, stimulating the synthesis of proteins and turnover of phospholipids.
Neuromet has no stimulant or sedative effects and does not affect the activity of the autonomous nervous system.
Clinical studies have shown it to improve acute and chronic cerebral performance (organic psychosyndrome), characterized for example by disorders in behavior, in time space orientation, in alteration, adaptation, and also to boost mental performance, including memory and learning.
Neuromet provides high bioreceptivity and optimum tolerance and may be taken in a wide range of dosages either by mouth or otherwise.
Recommendations
Mental syndromes having to do with cerebral activity, and mental performance disorders in the elderly.
Directions
Neuromet enables the patient to adapt the dosage to his own individual symptoms and response to treatment.
The form of administering this product (by mouth or injection) may be chosen according to the dosage to be taken the duration of the treatment and general conditions of the patient. The usual dosage is 800mg twice daily (morning and evening). During the maintenance treatment, the daily dosage may be reduced or increased, according to your physician's advice.
Contraindications
Individual hypersensitive to the product. Serious renal insufficiency.
Precautions
In the case of renal insufficiency, the product should be administered with caution and the dosage lowered.
Side Effects
Very rare cases have been reported of increased psychomotor excitability and sleep disorders due to an excessive reaction on the part of the patient to the product. In this case, the patient need only reduce the dosage.
Warning
This product should not be taken by women who are pregnant or who believe they might be. Keep out of children's reach