部分中文依托咪酯处方资料(仅供参考)
【中文品名】依托咪酯
【药效类别】注射麻醉药
【通用药名】ETOMIDATE
【别 名】Amidatem Hypnomidat, Hypnomidate, Hypnomidato, Nalgol, R-16659, Radenarcon, Sibul
【化学名称】1H-Imidazole-5-carboxylic acid, 1-(1-phenylethyl)-, ethyl ester
【CA登记号】[33125-97-2]
【结 构 式】
【分 子 式】C14H16N2O2
【分 子 量】244.29
【收录药典】
【开发单位】Janssen
【首次上市】1977年,德国
【性 状】
【用 途】
是一种短效注射用麻醉药。本品用于诱导麻醉,通常与芬太尼联合用于预防肌肉痉挛
其他名称:宜妥利
主要成分:
性状:乳剂。
功能主治:
全身麻醉诱导(短期麻醉须与镇痛药合用)。
用法及用量:
成人:150-300ug/kg体重,静注,15岁以下儿童和老年人150-200ug/kg体重,静注。肝硬化病人和曾用精神抑制药的病人须减少剂量。
不良反应和注意:
一次性剂量可使肾上腺皮质对紧张刺激的反应明显减慢约4-6小时。持续使用本药可能出现暂时性肾上腺皮质功能低下。没有接受过适当前驱给药的病人,使用单剂量后可能出现肌阵挛。偶有恶心,呕吐。一些病例可能出现咳嗽、呃逆和寒颤。个别病例可出现喉痉挛。大剂量使用本药或与中枢神经抑制剂合用时,偶见短暂呼吸暂停。
处方
其它:六个月以内的新生儿和婴幼儿。哺乳妇女禁用
Etomidate-®Lipuro IV hypnotic with outstanding local and systemic tolerance
Description
During its more than 40 years of clinical use, etomidate has been the induction anesthetic of choice. It is especially favourable in high-risk patients with cardiovascular instability, and emergency situations where the medical history of the patient is unknown. Previously known side effects like injection pain or vein irritation have been eliminated by the latest generation etomidate. Now Etomidate-®Lipuro is an even better choice for you and your patients.
Advantages
No pain on injection
No thrombophlebitis
Minimal cardiovascular effects
Ready-to-use: No pre-dissolving or dilution necessary
Indication
Induction of general anesthesia
Properties
Lipuro® inside - The innovative Etomidate-®Lipuro is based on the original B. Braun Lipuro®-Technology, which uses an MCT/LCT lipid emulsions as the drug carrier system for the sedative agent etomidate
Does not contain antimicrobial preservations
Presentation: 10 ml glass ampoule
Note
Information may differ in your country. Before prescribing refer to nationally approved prescribing information.