部分中文ENLON处方资料（仅供参考）
中文名称：依酚氯铵
英文名称：edrophonium chloride
药品别名：腾喜龙、艾宙酚、Tensilon、Enlon、Enlon-Plus、Reversol、Camsilon
药物剂型：注射剂
药理作用：属季铵类易逆性抗胆碱酯酶药。作用同新斯的明。
药动学：对骨骼肌的兴奋作用强大，作用快速而短暂。注射后30～60秒即可出现作用，维持时间10分钟左右。Vd为1.1士0.2L/kg，t1/2为1.8土0.6小时。
适应证：
(1)作为重症肌无力诊断剂：重症肌无力病人用药后，症状迅速改善，肌强度增加，作用维持5～15分钟后，恢复至原先的症状与体征。采用步骤为：静脉注射2mg，30～45秒内无不良反应，继续注射8mg。英国推荐儿童用药总量100μg/kg。开始采用剂量的1/5，若无不良反应，再给以余量。美国建议儿童用量：体重在34kg以下者，总量5mg，体重较重者为10mg。开始用剂量的1/5，每隔30～45秒增加1mg。静脉给药困难时可采用肌内注射，成人剂量10mg；儿童体重34kg以下用量2mg，体重较重者5mg。进行试验时，必须备有阿托品，以便及时处理严重的M胆碱受体兴奋症状。
(2)鉴别诊断重症肌无力用药过量或用量不足：用量不足者，用依酚氯铵后可使症状很快改善；若肌力下降，表踢抗胆碱酯酶药用药过量。
(3)解救非去极化型肌肉松弛药过量。
禁忌证：
有肠或尿道梗阻者禁用，患支气管哮喘及心脏病者慎用。
不良反应：
流涎、恶心、呕吐、腹痛、腹泻、尿频、支气管痉挛、心动过缓、心律失常等。
Enlon
Generic Name: edrophonium chloride
Dosage Form: injection, solution
Enlon Description
Enlon is a short and rapid-acting cholinergic drug. Chemically, edrophonium chloride is ethyl(m-hydroxyphenyl) dimethylammonium chloride and its structural formula is:
What is Enlon (edrophonium)?
Edrophonium is used as part of a medical test to help diagnose a muscle disorder called myasthenia gravis.

Edrophonium is sometimes used to reverse the effects of certain medications used to prevent muscle contractions during surgical procedures.

Edrophonium may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Enlon (edrophonium)?
You should not receive edrophonium if you have a blockage in your intestines, or if you are unable to urinate.
What should I discuss with my health care provider before receiving Enlon (edrophonium)?
You should not receive edrophonium if you are allergic to it, or if you have:

•a blockage in your intestines; or

•if you are unable to urinate.

To make sure edrophonium is safe for you, tell your doctor if you have:

•asthma;

•a heart rhythm disorder; or

•if you are allergic to sulfites.

It is not known whether edrophonium will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is edrophonium given?
Edrophonium is injected into a muscle, or into a vein through an IV. A healthcare provider will give you this injection.

When used in testing for myasthenia gravis, edrophonium is given in small doses over 15 to 45 seconds. After each dose you will be observed for certain reactions to this medicine (muscle twitching, vision changes, increased muscle weakness, sweating, stomach cramps, nausea, and other symptoms). You may receive other medications to treat the reaction to edrophonium.

The test you are receiving may be repeated a second time.

Your specific edrophonium test may be performed in a different manner than described above.

What happens if I miss a dose?
Since edrophonium is given by a healthcare professional, it is not likely that you will miss a dose.

What happens if I overdose?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving Enlon (edrophonium)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Enlon (edrophonium) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

•slow heartbeats, weak or shallow breathing, feeling like you might pass out;

•vision problems, eye redness or watering;

•seizure (convulsions);

•trouble speaking or swallowing;

•cough with mucus, wheezing, feeling short of breath;

•increased salivation, nausea, vomiting, diarrhea, stomach pain;

•muscle weakness, twitching or involuntary movement;

•increased sweating, urinating more than usual; or

•loss of bowel or bladder control.

Common side effects (some of which can be expected as part of a positive test reaction) may include:

•watery eyes, vision problems;

•changes in your voice;

•mild nausea, vomiting, diarrhea, stomach pain;

•weakness; or

•muscle twitching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088