部份中文双氢睾酮处方资料（仅供参考）
英文名：Dihydrotestosterone
商品名：Andractim DHT 2.5% Gel
中文名：双氢睾酮（又称二氢睾酮）
生产商：法国Besins公司
药品简介
Andractim DHT 2.5% Gel（Dihydrotestosterone 中文译名：双氢睾酮凝胶）是一种高效外用新药，主要用于治疗先天阴茎短小疾病。
作用
睾酮可直接或先转变为活性更强的双氢睾酮,与生精细胞的雄激素受体结合,促进精子的生成.所以,双氢睾酮的作用主要是有：
1.维持产生精子作用；
2.刺激生殖器官的发育,促进男性第二性征出现并维持其正常形态；
3.维持正常的性欲；
4.促进蛋白质的合成,特别是肌肉和生殖器官的蛋白质的合成,同时还能促进骨骼生长与钙磷的沉积和红细胞的生成。





【药品说明】
剂型：外用凝胶。
适应症：
治疗男子女性乳房发育、小阴茎、性腺功能减退、降低分解代谢，例如艾滋病引起的消瘦、女性硬化萎缩性苔藓，以及男性避孕。
【特点】
5a-双氢睾酮是天然产生的活性最强的雄性激素，在体内的生物活性是睾酮的6倍。睾酮在体内发挥生理作用主要通过在靶细胞代谢为双氢睾酮。双氢睾酮透皮吸收凝胶在1982年上市，由Laboratoires Besins International公司(Paris, France)开发，对于皮肤没有刺激性，最初双氢睾酮凝胶用于治疗男子女性乳房发育、小阴茎以及女性硬化萎缩性苔藓，后来适应症扩大，可以用于治疗性腺功能减退和降低分解代谢，例如艾滋病引起的消瘦，以及男性避孕。现在，一种新的0.7%双氢睾酮凝胶制剂正在进行III期临床实验。和目前广泛使用的睾酮及其衍生物相比较，双氢睾酮由于在体内不能转化成雌二醇，所以双氢睾酮不会产生男子女性乳房发育的副作用；并且在临床研究中发现，双氢睾酮可以使老年男性性腺功能减退患者前列腺的体积变小，所以，双氢睾酮与目前上市的睾酮及其衍生物相比较，有相对的优点。
提示：
Andractim DHT Gel（双氢睾酮2.5%凝胶）已恢复订购，需要者请速下单。
Andractim 2.5% gel
Andractim 2.5% gel is a synthetic version of a hormone called testosterone. It is prescribed in gel form at Great Ormond Street Hospital (GOSH) for children with hormone deficiencies.    
Andractim is not available in the UK so has to be imported from abroad.
It works by correcting the hormone deficiency, either in a particular part of the body or affecting the body as a whole.
How is andractim 2.5% gel used?
Andractim 2.5% gel is for external use only. Please follow the directions on the packaging. It should be spread over the affected area of skin after washing. The gel should be left to dry for five minutes or so before putting on clothes.
1.Put on a pair of gloves.
2.Squeeze the required amount of gel onto the spatula included in the package.
3.Spread over the affected area evenly.
4.Leave for five minutes.
5.Wash spatula and gloves in warm soapy water ready for the next dose.
Note: Andractim 2.5% gel should not be applied to any broken areas of skin.
Who should not use andractim 2.5% gel?
People who are hypersensitive to andractim 2.5% gel or its ingredients should discuss using this medicine with their doctor.
What are the side effects of andractim 2.5% gel?
The following side effects are rare and are usually due to the dose of androgen being too high, so will disappear when the dosage is reduced.
•mood swings and irritability
•excessive energy or signs of being hyperactive
•weight gain
•extra hair growth
•hoarseness
•oily skin
•acne
Andractim 2.5% gel and other medicines
Andractim 2.5% gel is applied externally so should not react with any other medicines.
Important information you should know:
•As this is a specialist treatment, GOSH or your local hospital will supply your child’s medicine. You will need to phone, as arranged, at least ten days before your supply runs out.
•Keep medicines in a safe place where children cannot reach them.
•Keep the gel at room temperature, away from bright light or direct sunlight and away from heat. Do not store in the fridge.
•If the doctor decides that your child should stop using andractim, return any remaining gel to your pharmacist. Do not throw away.