部份中文溴芬酸处方资料（仅供参考）
英文名：bromfenac Ophthalmic Solution
商标名：Xibrom
中文名：溴芬酸眼用溶液
生产商：ISTA Pharmaceuticals, Inc.
药品简介 FDA批准了0.09％溴芬酸钠眼用溶液（Xibrom，由ISTA Pharmaceuticals，Inc制造）的补充适应症，用于减少白内障摘除患者的眼痛。
作用机制：
Bromfenac是一种具有抗炎活性的非甾体类抗炎药（NSAID）。其作用机制被认为是由于其通过抑制环加氧酶1和2来阻断前列腺素合成的能力。
前列腺素已在许多动物模型中显示为某些种类的眼内炎症的介质。 在动物眼中进行的研究中，前列腺素已被证明会破坏血液 - 房水屏障，血管舒张，血管通透性增加，白细胞增多和眼压升高。
适应症
Xibrom（bromfenac）眼用溶液0.09％用于治疗白内障手术患者的术后炎症和减轻眼痛。
剂量和给药
推荐剂量
在白内障手术后24小时开始，每天两次向受影响的眼睛施用一滴Xibrom眼用溶液，并持续到术后前2周。
与其他外用眼科药物一起使用
Xibrom眼用溶液可以与其他局部眼用药物联合给药，例如α-激动剂，β-阻断剂，碳酸酐酶抑制剂，睫状体麻痹剂和散瞳剂。滴剂应至少间隔5分钟施用。
如何提供
剂型和优势
局部眼用溶液：溴芬酸0.09％。
存储和处理
Xibrom（溴芬酸眼用溶液）0.09％在白色LDPE塑料挤压瓶中提供，其具有15mm LDPE白色滴管尖端和15mm聚丙烯灰色帽，如下：
在7.5mL容器中加入2.5mL（NDC 67425-004-12）
10mL容器中的5mL（NDC 67425-004-50）
存储
储存在15°-25°C（59°-77°F）
Bromfenac sodium eye drops were developed by Senju Corporation of Japan and marketed in Japan in 2000 under the trade name BRONUCK® OPHTHALMIC SOL UTION. It is a 5ml/spray of 0.1% bromfenac sodium ophthalmic solution. Twice a day, symptomatic treatment for inflammatory diseases of the external eye and anterior eye: orbital inflammation, conjunctivitis, strong film inflammation (including upper tympanic inflammation), postoperative inflammation, etc. A phase III clinical study of ocular inflammation, pain, and photophobia after cataract surgery has been completed in the United States. A new drug application was filed with the FDA in the second quarter of 2004 and is now available in the US under the trade name XibromTM in early March 2005. . Sodium bromfenac is one of the derivatives of 2-amino-3-benzoylphenylacetic acid, the chemical name is sodium 2-amino-3-(4-bromobenzoyl)phenylacetate, and the structure is related to ketoprofen and diclofenac Similarly, it inhibits cyclooxygenase-mediated synthesis of prostaglandins inflammatory mediators and is the most potent cyclooxygenase inhibitor with potent anti-inflammatory and analgesic effects. The strength of action is other non-steroidal anti-inflammatory drugs (N 10 times that of SAIDs). https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021664s010lbl.pdf
