部份中文头孢甲肟盐酸盐处方资料（仅供参考）
英文名称：Cefmenoxime Hydrochloride
商品名称：BESTRON FOR OPHTHALMIC 0.5％
中文名称：头孢甲肟盐酸盐
剂    型：滴眼液
生产厂家：千寿药业
药物分类名称
Cephem抗生素制剂
批准日期：2007年12月
商標名
BESTRON FOR OPHTHALMIC 0.5％
一般名
セフメノキシム塩酸塩
（Cefmenoxime Hydrochloride）〔JAN〕　略号：CMX
化学名
（6R, 7R ）-7-［（Z ）-2-（2-Aminothiazol-4-yl）-2-（methoxyimino）acetylamino］-3-（1-methyl-1H -tetrazol-5-ylsulfanylmethyl）-8-oxo-5-thia-1-azabicyclo［4.2.0］oct-2-ene-2-carboxylic acid hemihydrochloride
構造式
分子式
（C16H17N9O5S3）2・HCl
分子量
1059.58
性状
盐酸头孢甲肟是白色至浅橙黄色晶体或结晶粉末。
它易溶于甲酰胺或二甲基亚砜，难溶于甲醇，极难溶于水，难溶于乙醇（95）。
滴度
当定量时，头孢甲肟盐酸盐每mg转化的脱水物含有890至975μg（效力）。 然而，该产物的效力表示为头孢甲肟（C16H17N9O5S3：511.56）的质量（效力）。
处理注意事项
存储方式
1.在室温下储存
2.融化后，存放在阴凉处，7天内使用。
药用药理学
1.抗菌作用
（1）对需氧和厌氧细菌的革兰氏阴性革兰氏阳性抗菌作用
铜绿假单胞菌，革兰氏阴性菌和金黄色变形杆菌等，链球菌属，显示出对革兰氏阳性菌肺炎链球菌很强的抗菌活性，其效果是杀菌（体外）。
（2）对临床分离株眼科抗菌作用
铜绿假单胞菌是从眼部感染患者中，流感嗜血杆菌，莫拉氏菌Rakunata（穆勒 - Axenfeld细菌），革兰氏阴性菌和奇异变形等，表皮葡萄球菌，链球菌属的金黄色葡萄球菌，肺炎球菌革兰氏阳性分离表现出在细胞中很强的抗菌活性（体外）。
（3）对实验性绿脓杆菌角膜感染的治疗效果
划伤鼠标，其中接种与绿脓杆菌（ET-1081,1082,1111）的临床分离株的角膜基质，最好罗恩眼睛确认角膜炎的发作（接种9-10小时）后下降0.5％或盐水作为对照，2滴在3天的滴眼剂每30分钟（第1天25次）进行了测试，以获得最佳罗恩滴注观察到抑制显著角膜病变的0.5％滴眼剂组的进展的影响。
（4）对实验性金黄色葡萄球菌角膜感染的治疗效果
创建与兔，一滴的妥布霉素耐药金黄色葡萄球菌角膜基质一次接种接种盐水作为0.5％或控制背心罗恩眼科后角膜感染，随后1小时后，1天9倍，滴眼液中测试7天，抑制最佳罗恩滴注0.5％滴眼剂组中观察到感染的症状的效果。
2.作用机制
作用机制是细菌细胞壁的合成的抑制。
适应症
<适应性真菌种类>
头孢甲肟敏感金黄色葡萄球菌，链球菌，链球菌，莫拉氏菌（Lacolata）（Moller和Acnfeld），粘质沙雷氏菌，变形杆菌，Morganella·Morganii，普罗维登西亚，流感嗜血杆菌，嗜血杆菌·埃及（Koch·Weeks） 细菌），铜绿假单胞菌，痤疮细菌
<适应症>
睑缘炎，泪囊炎，口腔炎，结膜炎，蜱上皮炎，角膜炎（包括角膜溃疡），眼科围手术期灭菌疗法
用法与用量
用附着的裂解液将该药物稀释至浓度为5mg（效力）作为头孢甲肟盐酸盐/1mL，并且每天一次滴加1至2滴，每天4次。
另外，根据症状适当地增加或减少次数。
但是，如果症状没有观察到改善，则不要连续长期连续给药。
临床结果
包括双盲对照对照研究在内的470例眼外感染疾病的结果总结如下。 每日剂量和给药期主要是2滴一次，每天4次，在4周内。
包装
25mg·溶解液5mL×5
制造供应商
千寿药业有限公司
销售：
武田制药有限公司
注：以上中文处方资料不够完整，使用者以原处方资料为准。
完整资料附件：http://www.info.pmda.go.jp/go/pack/1317713Q1038_1_05/ 
BESTRON FOR OPHTHALMIC 0.5%  5ml
Manufacturer's name : Senju Pharmaceutical Co.,Ltd. 620006517
Revised: 01/2011
Brand name : BESTRON FOR OPHTHALMIC 0.5%
　Active ingredient: Cefmenoxime hydrochloride
　Dosage form: white to orangish pale yellow powder, clear and colorless solvent,
after dissolution; clear and colorless to pale yellow ophthalmic solution,
(solvent bottle) with large white cap and small pink cap
　Printings on wrapping:
Effects of this medicine
This medicine inhibits synthesis of bacterial cell wall, and shows antibacterial action.
It is usually used in the treatment of eye infections such as conjunctivitis and hordeolum (sty), and for the sterilization before and after eye surgery.
Before using this medicine, tell your doctor/pharmacist
If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you or your family member have/ has a tendency to develop allergic symptoms such as bronchial asthma, rash and urticaria.
If you wear contact lenses.
If you are pregnant or breastfeeding.
If you are using any other prescription or nonprescription (OTC) medicine. (It is important to reduce the risk of drug interactions.)
Dosage regimen (proper use of this medicine)
Your dosage regimen is:(order of your doctor)
General dosage regimen: Dissolve 1 vial into 5 mL of the attached solvent. Apply 1 to 2 drops at a time, 4 times daily. The dosage may be adjusted according to the symptoms. Strictly follow the instructions of your doctor/pharmacist.
Push up the upward arrow (↑) on the powder vial and remove the top. Unscrew the large white cap of the solvent bottle. Insert firmly the bottle into the vial, not to spill the solvent, and then shake them well to dissolve the powder completely. After pouring the dissolved medicine into the bottle, remove the vial and recap the bottle tightly.
When using the medicine, remove the small pink cap only. Then apply the medicine making sure that the tip of eyedropper does not touch the eye.
Missed dose: If you remember that you missed a dose, apply a dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT apply double doses to make up for the missed dose.
Overdose: If you used too much of the medicine (more than ordered), check with your doctor/pharmacist.
Others: Do not stop using the medicine without the instructions of your doctor.
Precautions while using this medicine
Side effects of this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: rash, urticaria, irritation in the eye, itching sensation in the eye, conjunctival congestion, blepharitis (eyelid inflammation), swelling and redness in the eyelid, etc.In rare cases, symptoms described below may be the sign of side effects indicated in brackets [ ]. If they occur, stop using your medicine and check with your doctor immediately.
facial pallor, cold sweat, orthostatic dizziness [shock]
Other side effects not listed here may occur. Check with your doctor/pharmacist if you have any worrisome symptom.
Storage and other information
Keep out of the reach of children.
Store at room temperature (1-30℃), away from direct sunlight.
After dissolution, store in a cold place (1-15℃), and use within 7 days.
Discard the remainder. Do not store them.