部份中文头孢呋辛酯处方资料（仅供参考）
CEFTIN (头孢呋辛酯[Cefuroxime Axetil]) 片, 供口服使用
CEFTIN (头孢呋辛酯[Cefuroxime Axetil]) 口服悬浮液
美国初步批准: 1987
最近的重大变化
急性支气管炎的慢性支气管炎和继发细菌感染的适应症及用法、急性细菌性加重及二次致病菌: 急性支气管肺炎继发细菌感染-已取出: 11/2016
CEFTIN 片剂量及用量: 急性支气管炎 removed:11/2016 继发细菌感染
口服 suspension:10/2017 CEFTIN 的用量与管理、制备与管理
作用机制
CEFTIN 是一种抗菌药物 [见临床药理学]。
适应症和用法
CEFTIN 是一种头孢菌素抗菌药物, 用于治疗因易感细菌引起的以下感染:
•Pharyngitis/扁桃体炎 (成人和儿科患者)
•Acute 细菌性中耳炎 (儿科患者)
•Acute 细菌性上颌窦炎 (成人和儿科患者)
•Acute 慢性支气管炎 (成人和儿科患者13岁及以上) 的细菌性加重
•Uncomplicated 皮肤和皮肤结构感染 (成人和儿科患者13岁以上)
•Uncomplicated 泌尿道感染 (成人和儿科患者13岁以上)
•Uncomplicated 淋病 (成人和儿科患者13岁以上)
•Early Lyme 疾病 (成人和儿科患者13年和更旧)
•Impetigo (儿科患者)
为了减少抗药性细菌的发展, 保持CEFTIN和其他抗菌药物的有效性, CEFTIN 应仅用于治疗或预防被证实或强烈怀疑是由细菌引起的感染。
剂量和管理
•Tablets 和口服悬浮液不是等效的, 因此不能在每毫克毫克的基础上替代。
•Administer 片剂有或没有食物。
•Administer 口服悬浮食品。
•Administer CEFTIN片剂或CEFTIN口服悬浮液剂量指南中所述。
剂型和强度
•Tablets: 250mg 和500mg
•For 口服悬浮液: 125毫克/5毫升, 250毫克/5毫升
禁忌
对 CEFTIN 或其他β‑lactams(如青霉素和头孢菌素)的已知过敏反应(如过敏)。
警告和预防措施
•Serious 过敏反应: 在发生严重反应时, 停止CEFTIN并进行适当的治疗。
•Clostridium 梭菌相关腹泻(CDAD): 如果腹泻发生, 评估病人的 CDAD。
不良反应
最常见的不良反应 (≥3%) CEFTIN 片是腹泻, 恶心/呕吐, Jarisch‑Herxheimer 反应, 和阴道炎 (早莱姆病)。
CEFTIN 的最常见不良反应 (≥2%) 为腹泻、不喜欢味觉、尿布疹和恶心/呕吐。
药物相互作用
•Oral 避孕药: 对肠道菌群的影响可能降低雌激素吸收, 降低口服避孕药的功效。
•Drugs 可以降低胃酸度, 降低 CEFTIN 的生物利用度。
•Coadministration 与丙磺舒增加系统性接触 CEFTIN, 因此不建议。
包装提供/存储和处理
CEFTIN 片, 250 毫克头孢呋辛 (作为头孢呋辛酯), 是白色的, capsule‑shaped, film‑coated 片刻有 "ES7" 一侧和空白的另一侧如下:
20片/瓶 NDC 0173-0387-00
CEFTIN 片, 500 毫克头孢呋辛 (作为头孢呋辛酯), 是白色的, capsule‑shaped, film‑coated 片刻有 "EG2" 一侧和空白的另一侧如下:
20片/瓶 NDC 0173-0394-00
将片剂存放在59°和30°c 之间 (86°F)。每次打开后, 安全地更换瓶盖。
CEFTIN 为口腔悬浮液提供干燥、白色至 off‑white、tutti‑frutti–flavored 粉。当定向重组时, 悬浮液提供相当于125毫克或250毫克的头孢呋辛 (如头孢呋辛酯) 每5毫升。它是提供琥珀玻璃瓶如下:
125 mg/5 毫升:
100‑mL 悬浮 NDC 0173-0740-00
250 mg/5 毫升:
50‑mL 悬浮 NDC 0173-0741-10
100‑mL 悬浮 NDC 0173-0741-00
重组前, 在2°和30°c 之间贮存干粉 (36°和 86°F)。
重组后, 立即在2°和 8°C (36°和 46°F) 之间贮存悬浮冷藏。10天后丢弃。
完整说明书附件：
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2f439b86-59d6-4350-aeb4-c904b3781db4
Omnicef Oral Suspension
Cefdinir - Prices & Information
OMNICEF ORAL SUSPENSION (CEFDINIR)
Omnicef Oral Suspension Description
Omnicef oral suspension is a cephalosporin antibacterial medicine prescribed to help fight off many bacterial infections in your body such as strep throat or tonsillitis, urinary tract infections and pneumonia. Omnicef oral suspension or Cefdinir generic is not effective for treating viral infections.
The role of cephalosporin drugs is to interfere with the enzymes needed by the bacteria to build their cell walls. Without intact cell walls, there is no protection and the contents of the cells leak out. This takes away the bacteria’s ability to grow and reproduce so they eventually die off.
Conditions Treated by Omnicef Oral Suspension
Certain bacterial infections such as pneumonia and bacterial meningitis can be life-threatening. The elderly, hospitalized patients and individuals with a chronic disease are at a high risk of bacterial infection. Pneumonia is an infection that inflames the air sacs in one or both lungs. The air sacs may fill with fluid or pus, causing cough with phlegm or pus, fever, chills, and difficulty breathing. A variety of organisms, including bacteria, viruses and fungi, can cause pneumonia. For most people, pneumonia can be treated at home with medication such as Omnicef oral suspension. But older adults, babies, and people with other diseases can become very ill. They may need to be hospitalized.
Omnicef oral suspension may also be prescribed to treat strep throat, a bacterial infection that causes pain and inflammation in the throat. Strep throat is caused by group A Streptococcus bacteria and may cause the following symptoms; fever, headache, trouble swallowing, swollen lymph nodes, and loss of appetite. Your doctor may recommend some over the counter pain relievers as well as Omnicef oral suspension to treat strep throat.
Skin infections caused by Staphylococcus aureus are the most popular infections and a favorite target of Omnicef oral suspension. A simple cut or scratch is all the bacterium need to find their way inside to start growing and multiplying. Because of the overuse of penicillin through the years, some bacteria have become resistant to it so many doctors recommend a cephalosporin drug such as Omnicef oral suspension.
Before You Use Omnicef Oral Suspension
To make sure you can safely take Omnicef oral suspension, be sure to tell your doctor if you have kidney disease, or a history of intestinal problems such as colitis. Omnicef oral suspension contains sugar which may increase blood sugar levels if you have diabetes. Consult your doctor or pharmacist for more information.
Warnings for Omnicef Oral Suspension
Avoid using antacids or mineral supplements that contain iron within two hours before or after taking Omnicef oral suspension. Antacids or iron can make it harder for your body to absorb Omnicef oral suspension or generic Cefdinir. The generic alternative is not manufactured by the company that makes the brand product.