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The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse effects (risks) as well as efficacies (benefits). It is important to minimize adverse effects and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
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Brand name :
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APOPLON POWDER 0.1%
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Dosage form:
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white powder
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Effects of this medicine
This medicine is rauwolfia alkaloids, acts on storage sites of nerve transmitter substances to ease strain, lowers blood pressure, and controls mental excitement, visual hallucination and delusion.
It is usually used in the treatment of various hypertension and schizophrenia.
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Before using this medicine, be sure to tell your doctor and pharmacist
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If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you are a patient with depression, depressive state, peptic ulcer, ulcerative colitis, or renal failure.
If you are receiving electroconvulsive treatment.
If you are a patient with convulsive disorders such as epilepsy, or have a history of these diseases.
If you have a history of bronchial asthma or allergic diseases.
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If you are pregnant or breastfeeding.
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If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
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Dosing schedule (How to take this medicine)
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Your dosing schedule prescribed by your doctor is << to be written by a healthcare professional>>
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General dosage regimen:
For hypertension, for adults, take 0.2 to 0.5 g (0.2-0.5 mg of the active ingredient) daily, in 1 to 3 divided doses. When the blood pressure goes down and becomes stable, take 100 to 250 mg (0.1-0.25 mg of the active ingredient) daily, as the maintenance dose, however, the dosage may be adjusted according to the age or symptoms. Strictly follow the instructions of your doctor/pharmacist.
For schizophrenia, for adults, initially take 0.2 to 2 g (0.2-2 mg of the active ingredient) daily, then the dosage may be adjusted according to the response of the patient to the medicine. Also, the dosage may be adjusted according to the age or symptoms. Strictly follow the instructions of your doctor/pharmacist.
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Take a dose as soon as possible when you remember that you missed a dose. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT take a double dose to make up for the missed dose.
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If you took too much of the medicine (more than ordered), check with your doctor/pharmacist.
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Do not stop taking the medicine without the instructions of your doctor.
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Precautions while taking this medicine
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The medicine may cause drowsiness or feeling of weakness. Avoid driving a car or operating dangerous machinery after taking the medicine.
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Possible adverse effects of this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: drowsiness, hyposexuality, nervousness, dizziness, headache, rash, bradycardia, gastric ulcer, thirst, diarrhea, anorexia, nausea, vomiting, loose stool, nasal stuffiness, malaise, etc.
The symptoms described below are rarely seen as initial symptoms of the adverse effects indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
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having no energy, being depressed or discouraged, sleepless [depression]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
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Storage conditions and other information
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Keep out of the reach of children. Store away from heat and moisture.
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Do not store the remainder and ask your pharmacist how to discard it.
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