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HUMIRA 20mg for S.C. Injection Syringe 0.4mL
2014-01-15 11:37:44 来源: 作者: 【 】 浏览:531次 评论:0
Manufacturer's name : Eisai Co., Ltd. 622093601
Newly-created: 11/2011
 
Brand name : HUMIRA 20mg for S.C. Injection Syringe 0.4mL
 Active ingredient: Adalimumab (genetical recombination)
 Dosage form: colorless limpid or slightly opalescent injectable solution in prefilled syringe
 Printings on wrapping:  

Effects of this medicine

This medicine suppresses function of TNF-α which is the major causative substance of juvenile idiopathic arthritis. TNF (tumor necrosis factor) is one of cytokines existing inside of the body even in a healthy one, and involved in activities of immunity and development of inflammation or pain.
It is usually used in the treatment of patients with active, polyarticular-course juvenile idiopathic arthritis who had insufficient response to conventional therapy.

Before using this medicine, tell your doctor/pharmacist

  • If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
    If you are a patient with infections such as plural sepses or suspected of them.
    If you are a patient with tuberculosis or a history of it.
    If you are a patient with demyelinating disease such as multiple sclerosis or a personal or a family history of it.
    If you are a patient with hematologic disease or a hepatitis B virus carrier.
    If you have just received live vaccine.
    If you have congestive heart failure.
  • If you are pregnant or breastfeeding.
  • If you are using any other prescription or nonprescription (OTC) medicine. (It is important to reduce the risk of drug interactions.)

Dosage regimen (proper use of this medicine)

  • Your dosage regimen is:(order of your doctor)
  •  
  • General dosage regimen:
    If the patient weight is 15 kg to less than 30 kg, inject 1 syringe (20 mg of the active ingredient) subcutaneously at a time, every two weeks. Strictly follow the instructions of your doctor/pharmacist.
  • Injection site should be changed every time you inject the medicine. Do not inject to sensitive area of skin, wound site, skin rash or a psoriasis lesion. Do not massage the subcutaneous injection site.
  • You need to inject in the area of at least 3 cm apart from the last injection site.
  • Missed dose: Consult your doctor if you missed an injection.
  • Overdose: If you injected too much of the medicine (more than ordered), check with your doctor/pharmacist.
  • Others: Do not stop injecting the medicine without the instructions of your doctor.

Precautions while using this medicine

  •  

Side effects of this medicine

Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: nasopharyngitis, rash, injection site reaction (erythema, itch, rash, bleeding, swelling), upper respiratory tract infection, etc.In rare cases, symptoms described below may be the sign of side effects indicated in brackets [ ]. If they occur, stop using your medicine and check with your doctor immediately.
  • chill, sudden high fever with shivering, cough, sputum [severe infections such as sepsis or pneumonia]
  • prolonged slight fever or cough (2 weeks or over), general malaise, weight loss [tuberculosis]
  • joint pain, muscular pain, skin eruption [lupus-like syndrome]
  • reduced vision, double vision, numbness, pain, paralysis [demyelinating disease]
  • breathing difficulty, urticaria, swelling around the eye or lip [severe allergic reaction]
  • malaise, loss of appetite, yellowness in the skin and/or the white of the eye [fulminant hepatitis, hepatic dysfunction, jaundice, hepatic insufficiency]
Other side effects not listed here may occur. Check with your doctor/pharmacist if you have any worrisome symptom.

Storage and other information

  • Keep the medicine out of the reach of children. Store it away from light and freeze, at temperature of 2 to 8 ℃.
  • Discard the remainder. Do not store them. Ask the pharmacist how to discard.
For further information, ask your doctor/pharmacist. "Kanjamuke Iyakuhin Guide" and Japanese package insert information (for medical professionals) is available on the website of Pharmaceuticals and Medical Devices Agency. 
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