HUMIRA 20mg for S.C. Injection Syringe 0.4mL
Manufacturer's name : Eisai Co., Ltd. |
622093601 |
Newly-created: 11/2011 |
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Brand name : |
HUMIRA 20mg for S.C. Injection Syringe 0.4mL |
Active ingredient: |
Adalimumab (genetical recombination) |
Dosage form: |
colorless limpid or slightly opalescent injectable solution in prefilled syringe |
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Effects of this medicine
This medicine suppresses function of TNF-α which is the major causative substance of juvenile idiopathic arthritis. TNF (tumor necrosis factor) is one of cytokines existing inside of the body even in a healthy one, and involved in activities of immunity and development of inflammation or pain.
It is usually used in the treatment of patients with active, polyarticular-course juvenile idiopathic arthritis who had insufficient response to conventional therapy. |
Before using this medicine, tell your doctor/pharmacist
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If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you are a patient with infections such as plural sepses or suspected of them.
If you are a patient with tuberculosis or a history of it.
If you are a patient with demyelinating disease such as multiple sclerosis or a personal or a family history of it.
If you are a patient with hematologic disease or a hepatitis B virus carrier.
If you have just received live vaccine.
If you have congestive heart failure.
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If you are pregnant or breastfeeding.
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If you are using any other prescription or nonprescription (OTC) medicine. (It is important to reduce the risk of drug interactions.)
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Dosage regimen (proper use of this medicine)
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Your dosage regimen is:(order of your doctor)
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General dosage regimen:
If the patient weight is 15 kg to less than 30 kg, inject 1 syringe (20 mg of the active ingredient) subcutaneously at a time, every two weeks. Strictly follow the instructions of your doctor/pharmacist.
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Injection site should be changed every time you inject the medicine. Do not inject to sensitive area of skin, wound site, skin rash or a psoriasis lesion. Do not massage the subcutaneous injection site.
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You need to inject in the area of at least 3 cm apart from the last injection site.
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Missed dose: Consult your doctor if you missed an injection.
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Overdose: If you injected too much of the medicine (more than ordered), check with your doctor/pharmacist.
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Others: Do not stop injecting the medicine without the instructions of your doctor.
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Precautions while using this medicine
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Side effects of this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: nasopharyngitis, rash, injection site reaction (erythema, itch, rash, bleeding, swelling), upper respiratory tract infection, etc.In rare cases, symptoms described below may be the sign of side effects indicated in brackets [ ]. If they occur, stop using your medicine and check with your doctor immediately.
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chill, sudden high fever with shivering, cough, sputum [severe infections such as sepsis or pneumonia]
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prolonged slight fever or cough (2 weeks or over), general malaise, weight loss [tuberculosis]
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joint pain, muscular pain, skin eruption [lupus-like syndrome]
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reduced vision, double vision, numbness, pain, paralysis [demyelinating disease]
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breathing difficulty, urticaria, swelling around the eye or lip [severe allergic reaction]
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malaise, loss of appetite, yellowness in the skin and/or the white of the eye [fulminant hepatitis, hepatic dysfunction, jaundice, hepatic insufficiency]
Other side effects not listed here may occur. Check with your doctor/pharmacist if you have any worrisome symptom. |
Storage and other information
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Keep the medicine out of the reach of children. Store it away from light and freeze, at temperature of 2 to 8 ℃.
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Discard the remainder. Do not store them. Ask the pharmacist how to discard.
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For further information, ask your doctor/pharmacist. "Kanjamuke Iyakuhin Guide" and Japanese package insert information (for medical professionals) is available on the website of Pharmaceuticals and Medical Devices Agency. |