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See related Xylocaine Injection inj information |
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Manufacturer |
AstraZeneca |
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Distributor |
Hong Kong: Zuellig/Macau: Four Star |
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Contents |
Lidocaine HCl |
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Indications |
Production of local or regional anaesth by infiltration techniques; IV regional anaesth, by peripheral nerve block techniques eg intercostal blocks; major plexus blocks eg brachial plexus blocks & by epidural & subarachnoid blocks.
Click to view Xylocaine Injection detailed prescribing infomation |
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Dosage |
The lowest dosage that results in effective anaesth should be used. Adult Infiltration 20 mL of 1% inj or 10 mL of 2% inj. Paravertebral nerve block 3-5 mL of 1% inj. Pudendal block 10 mL of 1% inj on each side. Paracervical block 10 mL of 1% inj. Stellate ganglion block Cervical: 5 mL of 1% inj. Lumbar: 10 mL of 1% inj. Epidural anaesth Thoracic: 10-20 mL of 1% inj. Lumbar: 5-10 mL of 2% inj. Lumbar or caudal epidural analgesia 10-20 mL of 1% inj.
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Overdosage |
View Xylocaine Injection overdosage for action to be taken in the event of an overdose. |
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Contraindications |
Known hypersensitivity to local anaesth of the amide-type, or methyl parahydroxybenzoate (MDV only). Not to be used for epidural or spinal anaesth in patients w/ uncorrected hypotension or w/ coagulation disorders or receiving anticoagulation treatment. Not to be used when there is inflammation &/or sepsis in the region of proposed inj or in the presence of septicaemia.
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Special Precautions |
Inj should always be made slowly w/ frequent aspirations. Debilitated, elderly or acutely ill patients. Patients w/ preexisting abnormal neurological conditions, severe bradycardia, cardiac conduction disturbances or severe digitalis intoxication, hepatic &/or renal impairment, genetic predisposition to malignant hyperthermia. Paracervical blocks during pregnancy. Avoid intravascular inj. Multiple-dose vials are not recommended for intrathecal anaesth.
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Adverse Drug Reactions |
CNS reactions, either excitatory or depressant. CV reactions, mainly depressant. Maternal hypotension. Rarely allergic reactions.
View ADR Monitoring Form |
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Drug Interactions |
Antiarrhythmic drugs, β-blockers, cimetidine, anticonvulsive agents eg phenobarb, primidone, carbamazepine & diphenylhydantoin, amiodarone, inhalational anaesth, skeletal muscle relaxants, structurally-related local anaesth.
View more drug interactions with Xylocaine Injection |
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Pregnancy Category (US FDA) |
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters). |
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Caution For Usage |
For caution against possible variation of physical aspect of medicine... click to view Xylocaine Injection detailed prescribing infomation |
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Storage |
View Xylocaine Injection storage conditions for details to ensure optimal shelf-life. |
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Description |
View Xylocaine Injection description for details of the chemical structure and excipients (inactive components). |
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Mechanism of Action |
View Xylocaine Injection mechanism of action for pharmacodynamics and pharmacokinetics details. |
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ATC Classification |
N01BB02 - lidocaine ; Belongs to the class of amides. Used as local anesthetics. |
