See related Zometa powd for inj information
Manufacturer Novartis
Distributor Hong Kong: Zuellig/Macau: Four Star
Contents Zoledronic acid
Indications Prevention of skeletal-related events (pathological fractures, spinal compression, radiation or surgery to bone, or tumour-induced hypercalcaemia) in patients w/ advanced bone malignancies. Treatment of hypercalcaemia of malignancy (HCM).
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Dosage Prevention of skeletal-related events in patient w/ advanced bone malignancies & HCM Adult & elderly Recommended dose: 4 mg IV infusion for not <15 min every 3-4 wk. Dilute the conc w/ 100 mL NaCl 0.9% or glucose soln 5%. Patient should also take oral Ca supplement 500 mg & vit D 400 IU daily. Hydrate patient prior to & following administration of Zometa.
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Overdosage View Zometa overdosage for action to be taken in the event of an overdose.
Contraindications Hypersensitivity to bisphosphonates. Pregnancy & lactation.
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Special Precautions Severe renal or hepatic impairment. Monitor serum electrolytes & creatinine. Assess hydration status prior to administration. Patient should maintain oral Ca supplement 500 mg & vit D 400 IU daily.
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Adverse Drug Reactions Rise in body temp, flu-like syndrome, bone ache, myalgia, GI discomfort, rash, pruritus, chest pain, local inj site reactions.
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Drug Interactions Aminoglycosides.
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Pregnancy Category (US FDA)
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Caution For Usage For caution against possible variation of physical aspect of medicine... click to view Zometa detailed prescribing infomation
Storage View Zometa storage conditions for details to ensure optimal shelf-life.
Description View Zometa description for details of the chemical structure and excipients (inactive components).
Mechanism of Action View Zometa mechanism of action for pharmacodynamics and pharmacokinetics details.
Presentation/Packing
Form Packing Photo
Zometa powder for injection Zometa 4 mg/5 mL x 1's
Manufacturer: Novartis

Distributor: Hong Kong: Zuellig

Macau: Four Star