Doptelet(avatrombopag Tablet)
DOPTELET Rx
Generic Name and Formulations:
Avatrombopag 20mg; tabs.
Company:
Dova Pharmaceuticals
Indications for DOPTELET:
Thrombocytopenia in adults with chronic liver disease who are scheduled to undergo a procedure.
Adult:
Start treatment 10–13 days prior to procedure; undergo procedure within 5–8 days after last dose. Take with food. Platelet count <40 x 109/L: 60mg once daily for 5 days; 40–<50 x 109/L: 40mg once daily for 5 days.
Children:
Not established.
Warnings/Precautions:
Obtain platelet count prior to treatment and on day of procedure. Increased thrombotic risk with known risk factors (eg, Factor V Leiden, Prothrombin 20210A, Antithrombin deficiency, Protein C or S deficiency). Do not use to normalize platelet counts. Pregnancy; may cause fetal harm. Nursing mothers: not recommended (during and for ≥2 weeks after last dose).
Pharmacological Class:
Thrombopoietin receptor agonist.
Adverse Reactions:
Pyrexia, abdominal pain, nausea, headache, fatigue, peripheral edema; thrombotic/thromboembolic complications.
Generic Availability:
NO
How Supplied:
Tabs—10, 15 |
