creased muscle mass) and anorexia associated with cancer.It has been well documented that cancer cachexia causes a significant impact on patients’quality of life and prognosis.To date, an effective treatment method for cancer cachexia has not yet been established.
Anamorelin is a selective, novel, orally active ghrelin receptor agonist. Ghrelin is an endogenous peptide primarily secreted by the stomach. Upon binding to its receptor, ghrelin stimulates multiple pathways in the positive regulation of body weight, muscle mass, appetite and metabolism.Anamorelin has shown effects in increasing body weight and muscle mass, as well as appetite in patients with cancer cachexia. |
