lete list of ingredients in TEGSEDI.
Before you start using TEGSEDI, tell your healthcare provider about all your medical conditions, including if you:
have or had bleeding problems.
have or had kidney problems.
are pregnant or plan to become pregnant. It is not known if TEGSEDI can harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if TEGSEDI can pass into your breast milk or harm your baby. Talk with your healthcare provider about the best way to feed your baby while you are using TEGSEDI.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Especially tell your healthcare provider if you take:
Vitamin A or beta-carotene supplements. Your healthcare provider should tell you to take vitamin A, but only take the amount they tell you to take.
blood thinners (anticoagulants) or medicines that affect blood clotting.
Ask your healthcare provider or pharmacist if you are not sure if you take any of these medicines. Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get a new medicine.
How should I use TEGSEDI?
Read the detailed Instructions for Use that come with your TEGSEDI.
Your healthcare provider will show you or your caregiver how to inject TEGSEDI the first time.
If you or your caregiver have any questions, ask your healthcare provider.
TEGSEDI is injected under your skin (subcutaneously) in your stomach area (abdomen), or the front of your upper legs (thighs) by you or a caregiver. A caregiver may also give you an injection of TEGSEDI in the outer area of your upper arm.
Do not inject into the same site each time.
Do not inject into the 2-inch area around the belly-button (naval).
Do not inject where the skin is bruised, tender, red, or hard.
Do not inject into areas with scars or tattoos.
Do not inject through clothing.
Follow your healthcare provider’s instructions on when to inject TEGSEDI.
TEGSEDI should be injected 1 time each week on the same day.
If you miss a dose, take the missed dose as soon as possible, unless your next scheduled dose is within 2 days. If your next scheduled dose is within 2 days, skip the missed dose and take your next scheduled dose on the scheduled day.
What are possible side effects of TEGSEDI?
TEGSEDI may cause serious side effects, including:
See “What is the most important information I should know about TEGSEDI?”
stroke. TEGSEDI may cause a stroke. One person taking TEGSEDI had a stroke, which occurred within 2 days after the first dose.Signs or symptoms of stroke may include:
sudden numbness or weakness especially on one side of the body
severe headache or neck pain
confusion
problems with vision, speech, or balance
droopy eyelids
Get emergency help immediately if you have symptoms of stroke.
inflammatory and immune system problems.Some people taking TEGSEDI had serious inflammatory and immune system problems. Symptoms of inflammatory and immune system problems included unexpected change in walking, weakness and spasms in legs, back pain, weight loss, headache, vomiting, and problems with speech.
liver effects. TEGSEDI may cause liver problems. Your healthcare provider should do laboratory tests to check your liver before you start TEGSEDI and while you are using it. Tell your healthcare provider if you have symptoms that your liver may not be working right, which could include unexpected nausea and vomi |
