ve quality of life by using it", while on the other hand lymphocytopenia develops over 500 μL of lymph Since the occurrence of PML is reported when prolonged prolapse occurs, it is necessary to monitor once every three months in such cases. Also, because it is converted from Th1 / Th17 to Th2, it causes serious recurrence when used for optic neuromyelitis (NMO). I urged attention that it is necessary to firmly discriminate between MS and NMO.
The clinical practice guidelines of MS are currently being revised and it is said that public comment is being recruited. The next revised version said that publication of the agent will not make it in time, but said it will respond by issuing additional information as needed from time to time
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