Left Ventricular Hypertrophy (LVH) is an enlargement of the walls of the left chamber of the heart (the heart’s main pumping chamber). LVH can happen from several things. High blood pressure is the most common cause of LVH.

Type 2 Diabetes with Nephropathy. Type 2 diabetes is a type of diabetes that happens mainly in adults. If you have diabetic nephropathy it means that your kidneys do not work properly because of damage from the diabetes.

Who should not take COZAAR?
Do not take COZAAR if you are allergic to any of the ingredients in COZAAR. See the end of this leaflet for a complete list of ingredients in COZAAR.

What should I tell my doctor before taking COZAAR?
Tell your doctor about all of your medical conditions including if you:

are pregnant or planning to become pregnant. See “What is the most important information I should know about COZAAR?”

are breast-feeding. It is not known if COZAAR passes into your breast milk. You should choose either to take COZAAR or breast-feed, but not both.

are vomiting a lot or having a lot of diarrhea

have liver problems

have kidney problems

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
COZAAR and certain other medicines may interact with each other. Especially tell your doctor if you are taking:

potassium supplements

salt substitutes containing potassium

water pills (diuretics)

medicines used to treat pain and arthritis, called non-steroidal anti-inflammatory drugs (NSAIDs), including COX-2 inhibitors.

How should I take COZAAR?
Take COZAAR exactly as prescribed by your doctor. Your doctor may change your dose if needed.

COZAAR can be taken with or without food.

If you miss a dose, take it as soon as you remember. If it is close to your next dose, donot take the missed dose. Just take the next dose at your regular time.

If you take too much COZAAR, call your doctor or Poison Control Center, or go to the nearest hospital emergency room right away.

What are the possible side effects of COZAAR?
COZAAR may cause the following side effects that may be serious:

Injury or death of unborn babies. See“What is the most important information I should know about COZAAR?”

Allergic reaction. Symptoms of an allergic reaction are swelling of the face, lips, throat or tongue. Get emergency medical help right away and stop taking COZAAR.

Low blood pressure (hypotension). Low blood pressure may cause you to feel faint or dizzy. Lie down if you feel faint or dizzy. Call your doctor right away.

For people who already have kidney problems, you may see a worsening in how well your kidneys work. Call your doctor if you get swelling in your feet, ankles, or hands, or unexplained weight gain.

The most common side effects of COZAAR in people with high blood pressure are:

“colds” (upper respiratory infection)

dizziness

stuffy nose

back pain

The most common side effects of COZAAR in people with type 2 diabetes with diabetic kidney disease are:

diarrhea

tiredness

low blood sugar

chest pain

high blood potassium

low blood pressure

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