aflet each time you refill your prescription, in case any information has changed. This leaflet provides only a summary of certain information about EMEND for Injection. Your doctor or pharmacist can give you an additional leaflet that is written for health professionals that contains more complete information. This leaflet does not take the place of careful discussions with your doctor. You and your doctor should discuss EMEND for Injection when you start taking your medicine.
What is EMEND for Injection?
EMEND for Injection is an antiemetic medicine for use in adult patients, to be given intravenously by your doctor. An antiemetic is a medicine used to prevent and control nausea and vomiting. EMEND for Injection is always used WITH OTHER MEDICINES to prevent and control nausea and vomiting caused by your chemotherapy treatment. EMEND for Injection is not used to treat nausea and vomiting that you already have.
Who should not take EMEND for Injection?
Do not take EMEND for Injection if you:
are taking any of the following medicines3:
ORAP® (pimozide)
SELDANE® (terfenadine)
HISMANAL® (astemizole)
PROPULSID® (cisapride)
Taking EMEND for Injection with these medicines could cause serious or life-threatening problems.
are allergic to fosaprepitant or any of the ingredients in EMEND for Injection. The active ingredient is fosaprepitant. See the end of this leaflet for a list of all the ingredients in EMEND for Injection.
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3 The brands listed are the registered trademarks of their respective owners and are not trademarks of Merck & Co., Inc.
What should I tell my doctor before and during treatment with EMEND for Injection?
Tell your doctor:
if you are pregnant or plan to become pregnant. It is not known if EMEND for Injection can harm your unborn baby.
if you are breast-feeding. It is not known if EMEND for Injection passes into your milk and if it can harm your baby.
if you have liver problems.
about all your medical problems.
about all the medicines that you are taking or plan to take, prescription and nonprescription medicines, vitamins, and herbal supplements. EMEND for Injection may cause serious life-threatening reactions if used with certain medicines (see the section Who should not take EMEND for Injection?). Some medicines can affect EMEND for Injection. EMEND for Injection may also affect some medicines, including chemotherapy, causing them to work differently in your body.
Your doctor may check to make sure your other medicines are working, while you are taking EMEND for Injection. Patients who take COUMADIN® (warfarin) may need to have blood tests after each 3-day treatment to check their blood clotting.
Women who use birth control medicines during treatment with EMEND for Injection and for up to 1 month after using EMEND for Injection should also use a back-up method of contraception to avoid pregnancy.
How should I take EMEND for Injection?
EMEND for Injection is given intravenously on Day 1 only of a 3-day regimen.
The recommended dose of EMEND for Injection is:
115 mg given intravenously 30 minutes before you start your chemotherapy treatment;
AND
One 80-mg capsule of EMEND2 (aprepitant) each morning for the 2 days following your chemotherapy treatment.
EMEND for Injection may be administered with or without food.
Tell your doctor if you already have nausea and vomiting bef |
