Especially tell your doctor if you take medicines for:

◦your immune system
◦cholesterol
◦infections
◦birth control
◦heart failure
◦HIV or AIDS
◦hepatitis C
◦gout
Also tell your doctor if you drink large amounts of grapefruit juice.

How should I take LIPTRUZET?

◦Take LIPTRUZET exactly as your doctor tells you to take it.
◦Your doctor will tell you how much LIPTRUZET to take and when to take it.
◦Your doctor may change your dose if needed.
◦Do not open your LIPTRUZET pouch until you are ready to take LIPTRUZET.
◦Take LIPTRUZET 1 time each day, with or without food. It may be easier to remember to take your dose if you do it at the same time every day, such as with breakfast, dinner, or at bedtime.
◦Tablets should be swallowed whole. Do not crush, dissolve, or chew tablets.
◦Keep taking LIPTRUZET unless your doctor tells you to stop. If you stop taking LIPTRUZET, your cholesterol may rise again.
◦If you miss a dose, do not take an extra dose. Just resume your usual schedule.
◦If you take too much LIPTRUZET, call your doctor or Poison Control Center at 1-800-222-1222 or go to the nearest hospital emergency room right away.
◦See your doctor regularly to check your cholesterol level and to check for side effects. Your doctor may do blood tests to check your liver before you start taking LIPTRUZET and during treatment.
What should I avoid while taking LIPTRUZET?

◦Do not start any new medicines before talking to your doctor. This includes prescription and non-prescription medicines, vitamins, and herbal supplements. LIPTRUZET and certain other medicines can interact causing serious side effects.
◦Do not drink more than 2 glasses of alcohol daily.
◦Do not get pregnant. If you get pregnant, stop taking LIPTRUZET right away and call your doctor.
What are the possible side effects of LIPTRUZET?

LIPTRUZET may cause serious side effects, including:

◦muscle problems. LIPTRUZET can cause serious muscle problems that can lead to kidney problems, including kidney failure. You have a higher chance for muscle problems if you are taking certain other medicines with LIPTRUZET.Tell your doctor right away if:
◦you have unexplained muscle pain, tenderness, or weakness, especially if you have a fever or feel more tired than usual, while you take LIPTRUZET.
◦you have muscle problems that do not go away even after your doctor has advised you to stop taking LIPTRUZET. Your doctor may do further tests to diagnose the cause of your muscle problems.
◦liver problems. Your doctor should do blood tests to check your liver before you start taking LIPTRUZET and if you have symptoms of liver problems while you take LIPTRUZET. Call your doctor right away if you have the following symptoms of liver problems:
◦feel tired or weak
◦loss of appetite
◦upper belly pain
◦dark urine
◦yellowing of your skin or the whites of your eyes
Also call your doctor right away if you have:

◦allergic reactions including swelling of the face, lips, tongue, and/or throat that may cause difficulty in breathing or swallowing which may require treatment right away
◦nausea and vomiting
◦passing brown or dark-colored urine
◦you feel more tired than