y to use LIPTRUZET
◦that after the foil pouch is opened, LIPTRUZET should be protected from moisture and light, and stored in a dry place
◦that for packages containing a plastic case (unit of use packages of 30 and 90), once they remove a tablet from the blister card, they should slide the blister card back into the plastic case
◦to discard any unused tablets 30 days after the pouch is opened
Tablets should be swallowed whole. Do not crush, dissolve, or chew tablets.
If a dose is missed, the patient should not take an extra dose. Just resume the usual schedule.
Manufactured by:
Merck Sharp & Dohme Corp., a subsidiary of
MERCK & CO., INC., Whitehouse Station, NJ 08889, USA
U.S. Patent Nos. 5,846,966 and RE37,721.
USPI-T-0653C1305R000
Patient Information
LIPTRUZET™ (LIP-true-zett)
(ezetimibe and atorvastatin)
Tablets
Generic name: ezetimibe and atorvastatin tablets
Read this information carefully before you start taking LIPTRUZET™ and each time you get more LIPTRUZET. There may be new information. This information does not take the place of talking with your doctor about your medical condition or your treatment. If you have any questions about LIPTRUZET, ask your doctor. Only your doctor can determine if LIPTRUZET is right for you.
What is LIPTRUZET?
LIPTRUZET contains 2 cholesterol-lowering medications, ezetimibe and atorvastatin.
LIPTRUZET is a prescription medicine used to lower levels of total cholesterol, LDL (bad) cholesterol and fatty substances called triglycerides in the blood. In addition, LIPTRUZET raises levels of HDL (good) cholesterol. LIPTRUZET is for patients who cannot control their cholesterol levels by diet and exercise alone. You should stay on a cholesterol-lowering diet while taking this medicine.
LIPTRUZET has not been shown to reduce heart attacks or strokes more than atorvastatin alone.
It is not known if LIPTRUZET is safe and effective in children.
Who should not take LIPTRUZET?
Do not take LIPTRUZET if you:
◦have active liver problems or repeated blood tests showing possible liver problems.
◦are allergic to ezetimibe or atorvastatin or any of the ingredients in LIPTRUZET. See the end of this leaflet for a complete list of ingredients in LIPTRUZET.
◦are pregnant or plan to become pregnant. LIPTRUZET may harm your unborn baby. If you are a woman of childbearing age, you should use an effective method of birth control while taking LIPTRUZET. Stop taking LIPTRUZET and call your doctor right away if you get pregnant while taking LIPTRUZET.
◦are breastfeeding or plan to breastfeed. LIPTRUZET can pass into your breast milk and may harm your baby. Talk to your doctor about the best way to feed your baby if you take LIPTRUZET. Do not breastfeed while taking LIPTRUZET.
What should I tell my doctor before taking LIPTRUZET?
Before you take LIPTRUZET, tell your doctor if you:
◦have a thyroid problem
◦have kidney problems
◦have diabetes
◦have unexplained muscle aches or weakness
◦drink more than 2 glasses of alcohol daily or have or have had liver problems
◦have any other medical conditions
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Taking LIPTRUZET with certain other medicines or substances can increase th