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See related Hydrea cap[愛治 膠囊] information |
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製造商 |
Bristol-Myers Squibb |
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代理/經銷商 |
Bristol-Myers Squibb |
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成份 |
Hydroxyurea |
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適應症 |
Melanoma, resistant chronic myelocytic leukemia, & recurrent, metastatic or inoperable carcinoma of the ovary. Local control of primary squamous cell (epidermoid) carcinomas of the head & neck (excluding lip) in conjunction with radiotherapy. |
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用量 |
Solid Tumors Intermittent therapy: 80 mg/kg as a single dose every 3rd day. Continuous therapy: 20-30 mg/kg as a single dose daily. Concomitant therapy with irradiation for carcinoma of the head, neck, & cervix 80 mg/kg as a single dose every 3rd day. Resistant chronic myelocytic leukemia Continuous therapy: 20-30 mg/kg as a single dose daily until intermittent therapy regimen has been eva luated. |
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過量 |
View Hydrea[愛治] overdosage for action to be taken in the event of an overdose. |
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美國食品藥物管理局之懷孕等級 |
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). |
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禁忌 |
Hypersensitivity. Bone marrow depression eg leukopenia, thrombocytopenia or severe anemia. Pregnancy & lactation. |
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注意事項 |
Previous or concomitant radiotherapy or cytotoxic therapy. Close monitoring for pancreatitis & hepatotoxicity is recommended in HIV patients. Severe anemia should be managed without interrupting hydroxyurea therapy. Elderly. The complete status of the blood, including bone marrow examination, kidney & liver function should be determined prior to & repeatedly during treatment. Hb level, total leukocyte & platelet counts should be performed at least once a week throughout the course of therapy. If WBC decreases to < 2500/mm3 or the platelet count to < 100,000/mm3, therapy should be interrupted. Marked renal dysfunction. |
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不良反應 |
Bone-marrow suppression; rarely, GI disorders, skin disorders, difficulty in micturition, alopecia. Headache, dizziness, disorientation, hallucination, seizure. Hematuria.
View ADR Monitoring Website[參閱藥物不良反應監測表格] |
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副作用 |
View Hydrea[愛治] side effects |
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交互作用 |
Other myelosuppressive agents or radiation therapy. Uricosuric medications.
View more drug interactions with Hydrea[愛治] |
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儲存 |
View Hydrea[愛治] storage conditions for details to ensure optimal shelf-life. |
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作用 |
View Hydrea[愛治] mechanism of action for pharmacodynamics and pharmacokinetics details. |
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本商品之市售規格 |
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劑型 |
包裝 |
圖片 |
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Hydrea 膠囊 |
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Hydrea 500 mg x 100's |
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Manufacturer: |
Bristol-Myers Squibb |
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Distributor: |
Bristol-Myers Squibb |
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