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See related Integrilin inj[應治凝 注射液] information |
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製造商 |
Schering-Plough |
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代理/經銷商 |
Schering-Plough |
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成份 |
Eptifibatide |
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適應症 |
Acute coronary syndrome (unstable angina or non-Q-wave MI). Percutaneous coronary intervention (PCI) including those undergoing intracoronary stenting. |
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用量 |
Acute coronary syndrome with creatinine clearance ≥50 mL/min 180 mcg/kg IV bolus as soon as possible after diagnosis, followed by a continuous infusion of 2 mcg/kg/min up to 72 hr or until discharge. If PCI is performed during Integrilin therapy, the infusion should be continued for up to 18-24 hr after the procedure or until discharge, allowing 96-hr therapy, <50 mL/min 180 mcg/kg IV bolus as soon as possible after diagnosis, followed by a continuous infusion of 1 mcg/kg/min. PCI with creatinine clearance ≥50 mL/min 180 mcg/kg IV bolus immediately before start of PCI, followed by a continuous infusion of 2 mcg/kg/min & a 2nd 180-mcg/kg bolus 10 min after the 1st bolus, continue infusion for up to 18-24 hr or until discharge, <50 mL/min IV bolus of 180 mcg/kg immediately before initiation of PCI followed by a continuous infusion of 1 mcg/kg/min & a 2nd 180 mcg/kg bolus 10 min after the 1st bolus, continue infusion for up to 18-24 hr or until discharge. |
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美國食品藥物管理局之懷孕等級 |
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters). |
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禁忌 |
GI bleeding, gross genitourinary bleeding or other active abnormal bleeding w/in previous 30 days of treatment. History of stroke, hemorrhagic stroke or diathesis, major surgery w/in past 6 weeks. Thrombocytopenia, prothrombin time (INR ≥2), severe HTN. Lactation. |
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注意事項 |
Hepatic impairment, renal failure. Pregnancy. Children. |
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不良反應 |
Bleeding, CV effects.
View ADR Monitoring Website[參閱藥物不良反應監測表格] |
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交互作用 |
Furosemide, streptokinase, heparin, oral anticoagulants, dipyridamole.
View more drug interactions with Integrilin[應治凝] |
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本商品之市售規格 |
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劑型 |
包裝 |
圖片 |
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Integrilin 注射劑 |
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Integrilin 0.75 mg/1 mL x 100 mL |
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Integrilin 2 mg/1 mL x 10 mL |
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Manufacturer: |
Schering-Plough |
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Distributor: |
Schering-Plough |
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