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健保碼及健保價 |
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See related Zestril tab[捷賜瑞 錠] information |
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製造商 |
AstraZeneca |
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代理/經銷商 |
Everbest |
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成份 |
Lisinopril dihydrate |
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適應症 |
Listed in Dosage. |
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用量 |
Hypertension Usual maintenance dose: 20 mg once daily. Starting dose: 10 mg once daily. Lower starting dose required in renal impairment, renovascular hypertension, vol or salt depletion when diuretics cannot be discontinued. Max: 80 mg/day. CHF 5-20 mg once daily. Starting dose: 2.5 mg. AMI 1st dose of 5 mg followed by 5 mg after 24 hr, 10 mg after 48 hr & then 10 mg once daily thereafter. Renal complications of diabetes mellitus 10-20 mg once daily. |
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過量 |
View Zestril[捷賜瑞] overdosage for action to be taken in the event of an overdose. |
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用法 |
May be taken with or without food |
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美國食品藥物管理局之懷孕等級 |
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). |
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禁忌 |
Angioedema associated with ACE inhibitors & in patients with hereditary or idiopathic angioedema. |
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注意事項 |
Symptomatic hypotension particularly in vol-depleted patients & CHF. Hypotension may occur during surgery/anesth. Patients with ischemic heart or cerebrovascular disease. Aortic stenosis or hypertrophic cardiomyopathy. Renal impairment. History of angioedema. Pregnancy, lactation. Anaphylactoid reactions reported in patients undergoing hemodialysis & desensitization treatments. |
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不良反應 |
Dizziness, headache, diarrhoea, fatigue, cough, nausea, rash, orthostatic effects, asthenia. Rarely, angioedema, MI, CVA possibly secondary to excessive hypotension in high risk patients, palpitations, tachycardia, abdominal pain and indigestion, dry mouth, hepatitis, jaundice, vomiting, mood alterations, mental confusion, vertigo, urticaria, diaphoresis, uraemia, oliguria/anuria, renal dysfunction, acute renal failure, impotence, a symptom complex which may include fever, vasculitis, myalgia, arthralgia/arthritis, positive ANA, elevated ESR, eosinophilia & leukocytosis. Rash, photosensitivity or other dermatological manifestations. Increases (usually reversible) in blood urea, serum creatinine, liver enzymes & serum bilirubin. Small decreases in hemoglobin & hematocrit. Hyperkalemia, hyponatremia, leucopenia, thrombocytopenia, bone marrow depression, manifest as anaemia, paraesthesia, pancreatitis. Rarely, haemolytic anaemia.
View ADR Monitoring Website[參閱藥物不良反應監測表格] |
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副作用 |
View Zestril[捷賜瑞] side effects |
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交互作用 |
Risk of hyperkalemia with K-sparing diuretics, K supplements, K-containing salt substitutes. Antihypertensive effect may be diminished by indomethacin. Additive antihypertensive effects with diuretics. May reduce lithium elimination. ACE inhibitors may potentiate the hypoglycaemic effect of insulin & oral anti-diabetic drugs.
View more drug interactions with Zestril[捷賜瑞] |
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儲存 |
View Zestril[捷賜瑞] storage conditions for details to ensure optimal shelf-life. |
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作用 |
View Zestril[捷賜瑞] mechanism of action for pharmacodynamics and pharmacokinetics details. |
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本商品之市售規格 |
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劑型 |
包裝 |
圖片 |
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Zestril 錠劑 |
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Zestril 5 mg x 28's |
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Zestril 10 mg x 28's |
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Manufacturer: |
AstraZeneca |
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Distributor: |
Everbest
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