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健保碼及健保價 |
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See related Alkeran[威克瘤] information |
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製造商 |
GlaxoSmithKline |
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代理/經銷商 |
GlaxoSmithKline |
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成份 |
Melphalan |
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適應症 |
Listed in Dosage. |
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用量 |
Tab Multiple myeloma 0.15 mg/kg/day in divided doses for 4 days repeated at intervals of 6 weeks. Advanced ovarian adenocarcinoma 0.2 mg/kg/day for 5 days. Repeated 4-8 weekly or as soon as peripheral blood count has recovered. Polycythemia vera Remission induction: 6-10 mg daily for 5-7 days, then 2-4 mg daily until satisfactory disease control achieved. Maintenance: 2-6 mg once weekly. Inj Multiple myeloma 0.4 mg/kg repeated at appropriate intervals (eg. Once 4 weekly). Advanced ovarian adenocarcinoma 1 mg/kg at 4-week intervals. In combination with other cytotoxic drugs, 0.3-0.4 mg/kg at intervals of 4-6 weeks. Malignant melanoma Upper extremity perfusion: 0.6-1 mg/kg. Lower extremity perfusion: 0.8-1.5 mg/kg. Soft tissue sarcoma Upper extremity perfusion: 0.6-1 mg/kg. Lower extremity perfusion: 1-1.4 mg/kg. Advanced neuroblastoma 100-240 mg/m2 body surface area (sometimes divided equally over 3 consecutive days). |
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用法 |
Should be taken on an empty stomach (Take on an empty stomach 1 hr before or 2 hr after meals. Swallow whole, do not break/crush.). |
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美國食品藥物管理局之懷孕等級 |
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). |
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禁忌 |
Pregnancy (1st trimester) & lactation. |
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注意事項 |
Monitor blood counts; patients who have recently received radiotherapy or other cytotoxic agents. Renal impairment. Ensure adequate contraceptive precautions. Should not administer into a peripheral vein. |
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不良反應 |
Bone marrow depression, thrombocytopenia, anemia; nausea, vomiting, diarrhea; stomatitis, alopecia, elevated blood urea.
View ADR Monitoring Website[參閱藥物不良反應監測表格] |
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交互作用 |
Avoid immunization with live vaccine. Nalidixic acid, cyclosporin.
View more drug interactions with Alkeran[威克瘤] |
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本商品之市售規格 |
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劑型 |
包裝 |
圖片 |
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Alkeran 錠劑 |
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Alkeran 2 mg x 25's |
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Alkeran 乾粉注射劑 |
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Manufacturer: |
GlaxoSmithKline |
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Distributor: |
GlaxoSmithKline |
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