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See related Nexavar film-coated tab information |
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Manufacturer |
Bayer HealthCare Pharma |
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Distributor |
DKSH |
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Contents |
Sorafenib |
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Indications |
Advanced renal cell carcinoma. Patients w/ hepatocellular carcinoma who are unable to undergo surgery & in whom local chemotherapy is unsuitable.
Click to view Nexavar detailed prescribing infomation |
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Dosage |
400 mg bid. Consult hepatobiliary cancer practice guidelines for more details.
Click to view Nexavar detailed prescribing infomation |
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Overdosage |
View Nexavar overdosage for action to be taken in the event of an overdose. |
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Administration |
Should be taken on an empty stomach (Take on an empty stomach or w/ a low or moderate fat meal. Swallow whole, do not chew/crush.). |
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Contraindications |
[Click for Nexavar detailed prescribing infomation] |
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Special Precautions |
Dermatological toxicities, HTN, hemorrhage, cardiac ischemia &/or infarction, wound healing complications, GI perforation, hepatic impairment. Pregnancy, lactation.
Click to view Nexavar detailed prescribing infomation |
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Adverse Drug Reactions |
Fatigue, wt loss, rash/desquamation, hand-foot skin reaction, alopecia, diarrhea, anorexia, nausea, abdominal pain.
View ADR Monitoring Form |
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Drug Interactions |
Warfarin, irinotecan, docetaxel, rifampicin, phenytoin, carbamazepine, phenobarb, dexamethasone, St. John's wort, doxorubicin.
View more drug interactions with Nexavar |
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Pregnancy Category (US FDA) |
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). |
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Storage |
View Nexavar storage conditions for details to ensure optimal shelf-life. |
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Description |
View Nexavar description for details of the chemical structure and excipients (inactive components). |
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Mechanism of Action |
View Nexavar mechanism of action for pharmacodynamics and pharmacokinetics details. |
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Presentation/Packing |
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Form |
Packing |
Photo |
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Nexavar film-coated tablet |
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Nexavar 200 mg x 6 x 10's |
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Manufacturer: |
Bayer HealthCare Pharma |
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Distributor: |
DKSH |
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