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See related Tygacil infusion information |
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Manufacturer |
Pfizer |
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Distributor |
Zuellig |
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Contents |
Tigecycline |
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Indications |
Treatment of complicated skin & skin structure infections, complicated intra-abdominal infections & community-acquired pneumonia caused by susceptible strains of microorganisms in patients ≥18 yr.
Click to view Tygacil detailed prescribing infomation |
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Dosage |
Initially 100 mg followed by 50 mg 12 hrly by IV infusion over approx 30-60 min. Duration of treatment: 5-14 days (complicated skin & skin structure infections) or 7-14 days (community-acquired pneumonia). Patients w/ severe hepatic impairment (Child-Pugh C) 100 mg followed by 25 mg 12 hrly.
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Overdosage |
View Tygacil overdosage for action to be taken in the event of an overdose. |
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Contraindications |
Hypersensitivity.
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Warnings |
For additional cautionary notes to warn of the potential risk of using the medicine... click to view Tygacil detailed prescribing infomation |
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Special Precautions |
Hypersensitivity to tetracycline class antibiotics. Anaphylaxis/anaphylactoid reactions, pseudomembranous colitis, may cause permanent tooth discoloration, complicated intra-abdominal infections secondary to clinically apparent intestinal perforation, hepatic dysfunction/failure, photosensitivity, pseudotumor cerebri, anti-anabolic action, pancreatitis, hospital-acquired pneumonia, overgrowth of nonsusceptible organisms may occur. May impair ability to drive or operate machinery. Patient <18 yr. Pregnancy & lactation.
Click to view Tygacil detailed prescribing infomation |
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Adverse Drug Reactions |
GI disturbances, prolonged prothrombin time & activated partial thromboplastin time, bilirubinemia, increased BUN, hypoproteinemia, hypoglycemia, dizziness, phlebitis, pneumonia, anorexia, elevated AST, ALT & serum amylase, pruritus, rash, headache, abnormal healing.
View ADR Monitoring Form |
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Drug Interactions |
Monitor prothrombin time when given w/ warfarin. May decrease effect of OC.
View more drug interactions with Tygacil |
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Pregnancy Category (US FDA) |
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). |
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Caution For Usage |
For caution against possible variation of physical aspect of medicine... click to view Tygacil detailed prescribing infomation |
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Storage |
View Tygacil storage conditions for details to ensure optimal shelf-life. |
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Description |
View Tygacil description for details of the chemical structure and excipients (inactive components). |
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Mechanism of Action |
View Tygacil mechanism of action for pharmacodynamics and pharmacokinetics details. |
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Presentation/Packing |
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Form |
Packing |
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Tygacil infusion |
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Tygacil 50 mg x 1 x 10's |
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Manufacturer: |
Pfizer |
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Distributor: |
Zuellig |
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