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Manufacturer AstraZeneca 
Distributor DKSH 
Contents Daptomycin
Indications Infections caused by gm +ve bacteria only. Complicated skin & skin structure infections, Staph aureus bacteremia including right-sided infective endocarditis, methicillin-susceptible & -resistant isolates in adults.
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Dosage IV infusion over 30 min. Adult Complicated skin & skin structure infections 4 mg/kg once every 24 hr for 7-14 days. Staphylococcus aureus bacteremia including right-sided endocarditis 6 mg/kg once every 24 hr for 2-6 wk. Patient w/ CrCl <30mL/min Increase dose interval to a single dose once every 48 hr.
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Overdosage View Cubicin overdosage for action to be taken in the event of an overdose.
Contraindications Hypersensitivity.
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Special Precautions Neuropathy, renal insufficiency. Monitor plasma creatine phosphokinase (CPK) & renal function. Discontinue in case of unexplained muscle symptoms if CPK is >1,000 u/L or if asymptomatic but CPK is >2,000 u/L. Lactation.
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Adverse Drug Reactions Anemia, eosinophilia, thrombocytosis, supraventricular arrhythmia, vertigo, GI disorders, fatigue, infusion site reactions, pyrexia, rigors, jaundice, fungal infections, UTI, decreased appetite, hyperglycemia, arthralgia, muscle pain/weakness, rhabdomyolysis, dizziness, headache, paresthesia, taste disorder, anxiety, insomnia, vaginitis, rash, pruritis, uriticaria, flushes, HTN, hypotension.
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Drug Interactions HMG-CoA reductase inhibitors, tobramycin, dextrose-containing diluents.
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Pregnancy Category (US FDA)      
     
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters). 
Caution For Usage For caution against possible variation of physical aspect of medicine... click to view Cubicin detailed prescribing infomation
Storage View Cubicin storage conditions for details to ensure optimal shelf-life.
Description View Cubicin description for details of the chemical structure and excipients (inactive components).
Mechanism of Action View Cubicin mechanism of action for pharmacodynamics and pharmacokinetics details.

Presentation/Packing
Form Packing Photo
Cubicin infusion  Cubicin 500 mg x 1's 
 
Manufacturer: AstraZeneca
 
Distributor: DKSH