See related Pariet film-coated tab information |
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Manufacturer |
Eisai |
Distributor |
DKSH |
Contents |
Rabeprazole Na |
Indications |
Active duodenal, active benign gastric & anastomotic ulcers, erosive or ulcerative GERD, GERD maintenance, symptomatic GERD, Zollinger-Ellison syndrome & other pathological hypersecretory conditions. In combination w/ appropriate antibacterial therapeutic regimens for eradication of H. pylori in patients w/ PUD.
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Dosage |
Adult & elderly Active duodenal, active benign gastric & anastomotic ulcers, erosive or ulcerative GERD & GERD maintenance 10-20 mg once daily. Symptomatic GERD 10 mg once daily. When symptom has resolved, use as on-demand regimen for subsequent symptom control. Short-term (up to 8 wk) treatment of GERD Adolescent ≥12 yr 20 mg once daily up to 8 wk. Zollinger-Ellison syndrome Individualized dosage. Initially 60 mg daily. Doses up to 100 mg daily or 60 mg bid have been used. Eradication of H. pylori Pariet 20 mg bid + clarithromycin 500 mg bid + amoxicillin 1 g bid for 7 days.
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Overdosage |
View Pariet overdosage for action to be taken in the event of an overdose. |
Administration |
May be taken with or without food (Swallow whole, do not chew/crush.). |
Contraindications |
[Click for Pariet detailed prescribing infomation] |
Special Precautions |
Exclude gastric or esophageal malignancy. Long-term treatment. Severe hepatic dysfunction. Pregnancy & lactation. Childn.
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Adverse Drug Reactions |
Headache, diarrhea, abdominal pain, asthenia, flatulence, rash & dry mouth.
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Drug Interactions |
Decreases ketoconazole or itraconazole plasma levels.
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Pregnancy Category (US FDA) |
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters). |
Storage |
View Pariet storage conditions for details to ensure optimal shelf-life. |
Description |
View Pariet description for details of the chemical structure and excipients (inactive components). |
Mechanism of Action |
View Pariet mechanism of action for pharmacodynamics and pharmacokinetics details. |
Special Feature |
Researched & developed in Japan by Eisai Co., LtdUS FDA Approved |
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