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See related Valdoxan film-coated tab information |
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Manufacturer |
Servier |
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Distributor |
Zuellig |
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Contents |
Agomelatine |
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Indications |
Major depressive episodes.
Click to view Valdoxan detailed prescribing infomation |
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Dosage |
Adult 1 tab once daily; may be increased after 2 wk to 2 tab once daily. All doses to be taken at bedtime.
Click to view Valdoxan detailed prescribing infomation |
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Overdosage |
View Valdoxan overdosage for action to be taken in the event of an overdose. |
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Administration |
May be taken with or without food |
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Contraindications |
Hepatic impairment. Concomitant potent CYP1A2 inhibitors eg fluvoxamine, ciprofloxacin.
Click to view Valdoxan detailed prescribing infomation |
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Special Precautions |
Renal impairment. Monitor liver function tests. History of mania or hypomania. Suicidal tendencies. Avoid alcohol. Galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption. Childn & adolescent <18 yr. Elderly ≥65 yr. Pregnancy, lactation.
Click to view Valdoxan detailed prescribing infomation |
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Adverse Drug Reactions |
Headache, dizziness, somnolence, insomnia, migraine; nausea, diarrhoea, constipation, upper abdominal pain; hyperhidrosis; back pain; fatigue; increase in ALAT &/or ASAT; anxiety.
View ADR Monitoring Form |
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Drug Interactions |
CYP2C9 & CYP1A2 inhibitors (eg fluvoxamine, ciprofloxacin, propranolol, grepafloxacin, enoxacin), oestrogens.
View more drug interactions with Valdoxan |
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Storage |
View Valdoxan storage conditions for details to ensure optimal shelf-life. |
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Description |
View Valdoxan description for details of the chemical structure and excipients (inactive components). |
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Mechanism of Action |
View Valdoxan mechanism of action for pharmacodynamics and pharmacokinetics details. |
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