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See related Enbrel pre-filled inj information |
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Manufacturer |
Pfizer |
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Distributor |
Zuellig |
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Contents |
Etanercept |
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Indications |
Reduction in signs & symptoms & inhibiting the progression of structural damage in patient w/ moderate-severe active RA. Reduction in signs & symptoms of moderate-severe active polyarticular-course juvenile idiopathic arthritis (JIA). Reduction in signs & symptoms of active psoriatic arthritis & active ankylosing spondylitis. Treatment of plaque psoriasis in childn & adult.
Click to view Enbrel detailed prescribing infomation |
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Dosage |
SC RA, psoriatic arthritis, ankylosing spondylitis Adult 50 mg/wk. Active polyarticular-course JIA Childn 4-17 yr 0.8 mg/kg/wk (up to max 50 mg/wk). Plaque psoriasis Adult 50 mg once wkly or 25 mg twice wkly 72-96 hr apart; or 50 mg twice wkly up to 12 wk followed by 50 mg once wkly or 25 mg twice wkly. Childn 8-17 yr 0.8 mg/kg once wkly (up to max 50 mg/wk) up to 24 wk.
Click to view Enbrel detailed prescribing infomation |
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Overdosage |
View Enbrel overdosage for action to be taken in the event of an overdose. |
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Contraindications |
Patient w/ sepsis or risk of sepsis. Serious active infection including chronic or localized infection.
Click to view Enbrel detailed prescribing infomation |
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Warnings |
For additional cautionary notes to warn of the potential risk of using the medicine... click to view Enbrel detailed prescribing infomation |
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Special Precautions |
Patient w/ history of recurring infection or w/ underlying conditions (in addition to RA) which may predispose to infection. History of blood dyscrasias; eva luate urgently if patient develops signs & symptoms suggestive of blood dyscrasias or infection. Live vaccines should not be given concurrently. eva luate risk/benefit before prescribing to patient w/ preexisting or recent onset of CNS demyelinating disease. Possible tendency toward worsening of CHF w/ or w/o identifiable precipitating factors. Pregnancy & lactation. Childn <4 yr.
Click to view Enbrel detailed prescribing infomation |
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Adverse Drug Reactions |
Mild to moderate inj site reaction, infections, allergic reactions, fever, pruritus.
View ADR Monitoring Form |
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Drug Interactions |
[Click for Enbrel detailed prescribing infomation]
View more drug interactions with Enbrel |
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Pregnancy Category (US FDA) |
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters). |
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Storage |
View Enbrel storage conditions for details to ensure optimal shelf-life. |
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Description |
View Enbrel description for details of the chemical structure and excipients (inactive components). |
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Mechanism of Action |
View Enbrel mechanism of action for pharmacodynamics and pharmacokinetics details. |
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Presentation/Packing |
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Form |
Packing |
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Enbrel pre-filled injection |
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Enbrel (syringe) 25 mg x 2's |
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Enbrel (syringe) 50 mg x 2's |
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Manufacturer: |
Pfizer |
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Distributor: |
Zuellig
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