|
See related Kuvan tab[錠劑] information |
|
|
|
製造商 |
Merck |
|
代理/經銷商 |
Merck |
|
成份 |
Sapropterin diHCl |
|
適應症 |
Reduce blood phenylalanine (Phe) levels in patients with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin- (BH4-) responsive Phenylketonuria (PKU). Used in conjunction with a Phe-restricted diet. |
|
用量 |
10 mg/kg/day once daily. |
|
注意事項 |
Active management of dietary Phe intake during therapy to ensure adequate Phe control & nutritional balance. Hepatic & renal impairment. Co-administration of drugs affecting folate metabolism (eg. methotrexate), drugs that affect nitric oxide-mediated vasorelaxation (eg. PDE-5 inhibitors such as sildenafil, vardenafil, or tadalafil) & levodopa. Pregnancy & lactation. |
|
不良反應 |
Headache, diarrhea, abdominal pain, upper respiratory tract infection, pharyngolaryngeal pain, vomiting & nausea.
View ADR Monitoring Website[參閱藥物不良反應監測表格] |
|
交互作用 |
Co-administration of drugs affecting folate metabolism (eg. methotrexate), drugs that affect nitric oxide-mediated vasorelaxation (eg. PDE-5 inhibitors such as sildenafil, vardenafil, or tadalafil) & levodopa.
View more drug interactions with Kuvan[Kuvan] |
|
本商品之市售規格 |
|
|
|
Manufacturer: |
Merck |
|
Distributor: |
Merck |
|
|
|
|
