设为首页 加入收藏

TOP

Sapresta granule 2%.0.25g(Aranidipine 阿雷地平颗粒)
药店国别  
产地国家 日本 
处 方 药: 是 
所属类别 0.25克/袋 105袋/盒 
包装规格 0.25克/袋 105袋/盒 
计价单位: 盒 
生产厂家中文参考译名:
大鹏药业
生产厂家英文名:
Taiho Pharmaceutical Co.Ltd
该药品相关信息网址1:
http://www.info.pmda.go.jp/go/pack/2149038D1044_1_04/
该药品相关信息网址2:
该药品相关信息网址3:
原产地英文商品名:
Sapresta(サプレスタ顆粒2%)0.25g/bag 105bag/box
原产地英文药品名:
Aranidipine
中文参考商品译名:
Sapresta(サプレスタ顆粒2%) 0.25克/袋 105袋/盒
中文参考药品译名:
阿雷地平
曾用名:
简介:

 

部份中文阿雷地平处方资料(仅供参考)
英文名:Aranidipine
商品名:Sapresta
中文名:阿雷地平
剂  型:胶囊,颗粒剂
生产商:大鹏药品工业
サプレスタカプセル5mg/サプレスタカプセル10mg/サプレスタ顆粒2%
药效分类名
持久性Ca抗衡剂
批准日期:2003年7月
商標名
Sapresta capsule 5mg
Sapresta capsule 10mg
Sapresta granule 2%
構造式
一般名
アラニジピン(Aranidipine:JAN)
化学名
(±)-Methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate
分子式
C19H20N2O7
分子量
388.37
融点
148~151℃
分配係数
3×102(1-オクタノール/水系溶媒、pH2~9)
性状
黄色的结晶或晶体的粉末,没有香味。
乙酮、吉克罗米汤或1 , 4-吉奥基山容易融化,不易溶于甲醇,不易溶解于乙醇(99.5),极难溶于吉埃尔乙醇,几乎不溶于水。
根据光线的不同而变化。
1、4-吉奥基山溶液(1→50)不表示旋光性。
安装上的注意
颗粒剂因为有效成分不稳定在颗粒中涂层,配药的时候请注意不要尽可能光。
药效药理
1.降压作用
(1)1天1次对高血压患者使用,不会对血压变化产生影响,直到第二天稳定的降压效果得到了认可。
(2)高血压自然发症、肾性高血压、乙酸脱氧、甲酸脱脂高血压和肾性高血压,在使用单次口服时,其用量依赖性的降压作用得到了承认。另外,中风易发病高血压自然发病用老鼠进行的22周混饵注射中,抑制血压上升,高血压性器官障碍(脑中风、心肌纤维化、增值性及坏死细动脉炎、恶性肾硬化症等)的发病,并抑制维持效果得到了认可。
2.对循环运动状态的作用
(1)以轻、中等症的高血压患者为对象,研究了循环活动的结果,结果,降压效果主要是由慢性血管抵抗(11~16%)所导致的。
(2)对使用高血压自然发病的口服,得到了肾血流量、尿量、尿中na+及k+排泄量的增加。
3.降压作用机制
(1)在摩根的主动脉标本,抑制了钙离子细胞内的流入,并在猪主动脉标本中,依赖于尼特仑克的受体。另外,在moumoute单离心室肌细胞中,抑制了内部的钙离子电流。
(2)本剂的主要作用机制是血管平滑肌细胞的钙通道作用,对细胞外比细胞内的钙离子流入的抑制,使血管平滑肌松弛,血管扩张并发挥其降压效果。
适应症
高血压症
用法与用量
作为araquines,第一次使用的剂量为5毫克,一般成年人每天服用5 ~10毫克的药物。另外,根据年龄和症状适当增减,但在效果不充分的情况下,一天最多可增加到20mg。
包装
胶囊
5mg
ptp包装:100胶囊(10胶囊×10)
10mg
ptp包装:100胶囊(10胶囊×10)
颗粒2%
:0.25g×105包,0.25g×525包,0.5g×105包,0.5g*525包
瓶包装:100g
制造销售元
大鹏药品工业股份有限公司
注:以上中文处方资料不够完整,使用者以原处方资料为准。
完整说明书附件:http://www.info.pmda.go.jp/go/pack/2149038D1044_1_04/ 
Product name Suppressor granule 2%
Main ingredient alanidipine
Classification name
Formulation Yellow-white to brown yellowish white granules
Pharmaceutical company Taiho Pharmaceutical Co., Ltd.
Efficacy By inhibiting the influx of calcium into vascular smooth muscle cells, it relaxes the vascular smooth muscle and extends the blood vessel to demonstrate antihypertensive effect.
It is usually used to treat hypertension.
Precautions of use Prior to using the medicine, allergic symptoms such as itching, rash may have appeared. Liver function disorder, kidney function disorder.
Pregnant or lactating
We are using other medicines (we may strengthen or weaken each other 's actions, so please pay attention to other drugs in use, including over - the - counter drugs).
Dosage regimen
Usually, adults take 0.25 g of the initial dose (5 mg as the main ingredient) once a day, and after that take 0.25 to 0.5 g (5 to 10 mg) once a day. It increases and decreases according to age and symptoms as appropriate. Please follow the directions given by your doctor.
When you forget to drink, when you notice, please drink as much as possible as soon as possible. However, please allow more than 8 hours until the next dose. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Never drink two doses at the same time.
Please consult your doctor or pharmacist if you drink too much accidentally.
Please do not stop drinking at your own discretion without your doctor's instructions.
Living attention
Dizziness and wobble may occur due to a decrease in blood pressure, so please pay attention to the operation of the car, the work at the high place, and the operation of the machine accompanied by danger.
Please do not drink with grapefruit juice as there is a possibility that the action of the medicine will be strengthened.
Side effect
Headache, hot flushes, hot flashes, hot sensation, palpitations, anemia, dizziness, dizziness, rash, etc. are reported as major side effects. If you notice such symptoms, please consult your doctor or pharmacist.
The following symptoms appear rarely and it is possible that it may be the initial symptom of side effects shown in [].
In such cases, please stop using it and get medical attention immediately.
There are no applicable items to be noted.
These side effects do not describe everything. If any other symptoms are noted besides the above, please consult your doctor or pharmacist.
Storage method Other
Keep out of the reach of children, away from light, high temperature and moisture.
If medicine remains, please discard it without storing it. For disposal please consult the pharmacy you received.
Medicines have side effects (risks) as well as effects (benefits). It is important to minimize side effects and maximize effect. For this, it is necessary to understand and cooperate with the patient who is using this medicine. 

】【打印繁体】【投稿】【收藏】 【推荐】【举报】【评论】 【关闭】 【返回顶部
分享到QQ空间
分享到: 
上一篇Sapresta granule 2%.0.25g(Aran.. 下一篇Suppressor capsule 10mg(Aranid..

相关栏目

最新文章

图片主题

热门文章

推荐文章