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DOBUPUM Injection 0.1% syringe(盐酸多巴酚丁胺注射器)
药店国别  
产地国家 日本 
处 方 药: 是 
所属类别 50毫升/注射器 1注射器 
包装规格 50毫升/注射器 1注射器 
计价单位: 注射器 
生产厂家中文参考译名:
协和发酵麒麟
生产厂家英文名:
Kyowa Hakko Kirin Co
该药品相关信息网址1:
http://www.info.pmda.go.jp/go/pack/2119404G5032_1_09/
该药品相关信息网址2:
该药品相关信息网址3:
原产地英文商品名:
DOBUPUM Injection(ドブポン注0.1%シリンジ)50ml/syringe 1syringes/box
原产地英文药品名:
Dobutamine hydrochloride
中文参考商品译名:
DOBUPUM(ドブポン注0.1%シリンジ)50毫升/注射器 1注射器/盒
中文参考药品译名:
盐酸多巴酚丁胺
曾用名:
简介:

 

部份中文多巴酚丁胺处方资料(仅供参考)
药品英文名
Dobutamine
药品别名
强心胺、杜丁胺、丁巴多胺、多胺丁巴、多丁胺
药物剂型
注射剂:200mg(2ml),250mg(5ml)。
药理作用
多巴酚丁胺主要激动心肌β1受体,对β2和α1受体较弱,不激动多巴胺受体,其主要特点是增加心肌收缩力作用较强,而增加心率作用较弱,很少引起心律失常。
药动学
口服无效,静脉注射后,于5min内起效,作用要持续5~10min。在体内,一部分药物可被代谢成无活性的代谢产物,一次用量的25%左右在肾上腺神经末梢被代谢成去甲肾上腺素。t1/2约为2min。主要经肾脏排出体外。
适应证
主要用于治疗急性心肌梗死并发的左侧心力衰竭,各种心脏病引起的难治或顽固性心力衰竭,心脏手术后低心排血量综合征,舒张功能不全性心力衰竭,伴有房室传导阻滞的心力衰竭及病窦综合征并心力衰竭。
禁忌证
梗阻性肥厚型心肌病患者禁用。忌与碱性药物混合使用。
注意事项
1.急性心肌梗死、动脉粥样硬化、高血压和甲亢患者慎用。
2.用药前应首先补充血容量,以纠正低血容量。药液浓度随用量和患者所需液体量而定,但不应超过5g/L。
3.用药期间应随时检查心率、血压、尿量及是否出现异位搏动等情况,然后调整用药速度和剂量。
不良反应
有心悸、恶心、头痛、胸痛、气短、皮肤坏死等,可能诱发各种心律失常及心绞痛。
用法用量
静脉注射:成人滴速为每分钟2.5~10μg/kg,个别情况可达40μg/kg。给药剂量应个体化,从小剂量开始,逐渐加量。
药物相应作用
1.与地高辛合用治疗心力衰竭有协同作用;但两药合用后易引起心律失常;故合用时应酌减剂量。
2.与多巴胺合用治疗心力衰竭和心源性休克,可取长补短获得良好治疗作用。两药合用可加速房室传导,故应慎用于心房纤颤和心房扑动的患者。
3.与硝普钠合用治疗心力衰竭有协同作用,有时本品与硝普钠、多巴胺合用治疗顽固性心力衰竭效果更好。
4.与硝酸甘油合用改善心功能。
5.与依诺西蒙合用,具有协同扩血管作用。
6.与三氯二烯合用于有潜在性心功能不全者,可避免在麻醉过程中发生心力衰竭。
Brand name : DOBUPUM Injection 0.1% syringe
 Active ingredient: Dobutamine hydrochloride
 Dosage form: injection
 Print on wrapping: 
Effects of this medicine
This medicine improves blood circulation by enhancing cardiac contractility and dilating vessels.
It is usually used to enhance cardiac contractility in patients with acute circulatory failure.
Before using this medicine, be sure to tell your doctor and pharmacist
•If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have heart disease or hypertension.
If you have suspected or confirmed diabetes mellitus.
•If you are pregnant or breastfeeding.
•If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
•Your dosing schedule prescribed by your doctor is <<to be written by a healthcare professional>>
•In general, this medicine is injected intravenously.
•Dosage is determined depending on symptoms and effects.
Precautions while taking this medicine
• Possible adverse reactions to this medicine
The most commonly reported adverse reactions include arrhythmia (rapid heartbeat, impaired consciousness, etc.), decreased blood pressure, excessively increased blood pressure, palpitation, chest discomfort, anginal pain (chest constriction), precordial feeling hot, shortness of breath. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Kyowa Hakko Kirin Co.,LtdInjection
Published: 7/2013 

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