Drug Class Description
Bisphosphonates
Generic Name
Risedronate sodium
Drug Description
Actonel Combi 35 mg + 1000 mg / 880 IU film-coated tablets + effervescent granules
Presentation
Film-coated tablet: Risedronate tablets: Oval, light-orange, film-coated tablet with RSN on one side and 35 mg on the other.Effervescent granules: Calcium carbonate/colecalciferol, white effervescent granules
Indications
Treatment of postmenopausal osteoporosis, to reduce the risk of vertebral fractures. Treatment of established postmenopausal osteoporosis, to reduce the risk of hip fractures.Actonel Combi is only intended for use in assessed patients for whom the amount of calcium and vitamin D3 included is considered to provide adequate supplementation
Adult Dosage
Aweekly unit of Actonel Combi consists of 1 Actonel 35 mg film-coated tablet and 6 calcium/vitamin D3 sachets in a box.
The recommended dose in adults is 1 Actonel 35 mg tablet on the first day followed on the next day by 1 calcium/vitamin D3 sachet daily for 6 days. This 7-day sequence is then repeated each week starting with Actonel 35 mg tablet.
Actonel 35 mg (light-orange tablet):
The Actonel 35 mg tablet should be taken orally on the same day each week.
The absorption of risedronate sodium is affected by food, thus to ensure adequate absorption, patients should take the Actonel 35 mg tablet
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breakfast: at least 30 minutes before the first food, other medicinal product or drink (other than plain water) of the day.
The tablet must be swallowed whole and not sucked or chewed. To aid delivery of the tablet to the stomach the Actonel 35 mg tablet is to be taken while in an upright position with a glass of plain water (>
