Main use Active ingredient Manufacturer
Vitamin B and C deficiency Vitamins B & C (injection) Archimedes Pharma UK Ltd
How does it work?
Pabrinex injections contain the water soluble vitamins B and C. Vitamins are substances that are required by the body in very small amounts to maintain normal body functions. Vitamin B is involved in many biological activities, such as the development and maintenance of the nervous system (brain and nerves) and the formation of blood cells. Vitamin C is an antioxidant and is responsible for maintaining healthy cell structure and producing an important protein, known as collagen, which is found in the skin, bone, cartilage and tendons.
Vitamins B and C cannot be produced by the body, and are therefore obtained soley from the diet. Vitamin B is commonly found in liver, eggs and milk and vitamin C in citrus fruits such as oranges and in certain vegetables.
Vitamin B and C deficiencies can arise from poor diet, particularly in alcoholism or psychiatric states, or in conditions where the body cannot effectively absorb nutrients from the gut (malabsorption) and also due to depletion caused by regular kidney (renal) haemodialysis. This can lead to vitamin deficiency causing severe conditions of the nervous system and blood disorders which can be life threatening. Hence Pabrinex is given by injection over a short period of time, to rapidly replace depleted vitamins.
There are two forms of Pabrinex injection: - one is solely for injecting into the veins (intravenous use) and the other for injecting into the muscle (intramuscular use).
What is it used for?
Severe vitamin B and C deficiency due to depletion or malabsorption.
Warning!
Severe allergic reactions (anaphylaxis) may occur with this medicine. This is characterised by warning signs of sneezing and asthma-like symptoms.
Not to be used in
No known conditions.
This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
There are no known harmful effects when this medicine is used by pregnant or breastfeeding mothers.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Low blood pressure (hypotension).
Pins and needles (paraesthesia).
Pain at the injection site.
An extreme allergic reaction (anaphylaxis).
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
How can this medicine affect other medicines?
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
Pyridoxine (vitamin B6) may increase the breakdown of levodopa, reducing its effectiveness, if it is not given in conjunction with a dopa-decarboxylase such as carbidopa.
Other medicines containing the same active ingredients
There are currently no other injectable forms vitamin B and C available in the UK.
