Drug Class Description

Alkylating cytotoxics.
Generic Name

Carboplatin
Drug Description

Solution in vials.
Presentation

Injection, carboplatin 10 mg /mL.
Indications

Treatment of advanced ovarian carcinoma of epithelial origin in (a) first line therapy, (b) second line therapy after other treatments have failed. Treatment of small cell carcinoma of the lung.

Child Dosage

Insufficient usage in paediatrics to allow dosage recommendations to be made.
Contra Indications

Severe pre-existing renal impairment (creatinine clearance <20mL/minute). Severely myelosuppressed patients. History of several allergic reactions to Paraplatin or other platinum- containing compounds. Lactation.

Special Precautions

Should be administered by individuals experienced in the individuals experienced in the use of antineoplastic therapy. See data sheet. Pregnancy.
Interactions

Nephrotoxic compounds.
Adverse Reactions

Myelosuppression. Renal toxicity. Nausea and vomiting. See data sheet.
Manufacturer

Bristol-Myers Squibb
Drug Availability

(POM)
Updated

24 June 2009