Drug Class Description
Macrolides.
Generic Name
Clarithromycin - infections
Drug Description
Klaricid Paediatric Suspension or Clarithromycin 125 mg/5ml Granules for Oral Suspension
Presentation
White to off - white granules for reconstitution.
Indications
Klaricid Paediatric Suspension or Clarithromycin 125 mg/5ml Granules for Oral Suspension is indicated for the treatment of infections caused by susceptible organisms. Indications include:Lower respiratory tract infections.Upper respiratory tract infections.Skin and skin structure infections.Acute otitis media.Klaricid Paediatric Suspension or Clarithromycin 125 mg/5ml Granules for Oral Suspension is usually active against the following organisms in vitro:Gram-positive Bacteria:Staphylococcus aureus (methicillin susceptible); Streptococcus pyogenes (Group A beta-haemolytic streptococci); alpha-haemolytic streptococci (viridans group); Streptococcus (Diplococcus) pneumoniae; Streptococcus agalactiae; Listeria monocytogenes.Gram-negative Bacteria: Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella (Branhamella) catarrhalis, Neisseria gonorrhoeae; Legionella pneumophila, Bordetella pertussis, Helicobacter pylori; Campylobacter jejuni.Mycoplasma: Mycoplasma pneumoniae; Ureaplasma urealyticum.Other Organisms:Chlamydia trachomatis; Mycobacterium avium; Mycobacterium leprae; Chlamydia pneumoniae.Anaerobes: Macrolide-susceptible Bacteroides fragilis; Clostridium perfringens; Peptococcus species; Peptostreptococcus species; Propionibacterium acnes.Klaricid Paediatric Suspension or Clarithromycin 125 mg/5ml Granules for Oral Suspension has bactericidal activity against several bacterial strains. These organisms include H. influenzae, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agalactiae, Moraxella (Branhamella) catarrhalis, Neisseria gonorrhoeae, Helicobacter pylori and Campylobacter species.The activity of clarithromycin against H. pylori is greater at neutral pH than at acid pH.
Adult Dosage
Recommended doses and dosage schedules:
The usual duration of treatment is for 5 to 10 days depending on the pathogen involved and the severity of the condition. The recommended daily dosage of Klaricid Paediatric Suspension or Clarithromycin 125 mg/5ml Granules for Oral Suspension in children is given in the following table and is based on a 7.5mg/kg b.i.d. dosing regime. Doses up to 500mg b.i.d. have been used in the treatment of severe infections.
KLARICID PAEDIATRIC SUSPENSION OR CLARITHROMYCIN 125 MG/5ML GRANULES FOR ORAL SUSPENSION DOSAGE IN CHILDREN
|
Dosage Based on Body Weight (kg) |
|
Weight*(kg) |
Approx Age (yrs) |
Dosage (ml bid |
Dosage per 5ml teaspoonful twice daily |
|
8-11 |
1 - 2 |
2.50 |
1/2 |
|
12-19 |
3 - 6 |
5.00 |
1.00 |
|
20-29 |
7 - 9 |
7.50 |
1 1/2 |
|
30-40 |
10 - 12 |
10.00 |
2.00 |
* Children < 8 kg should be dosed on a per kg basis (approx. 7.5 mg/kg bid)
Preparation for use:140ml bottle:
