Drug Class Description
Antiglutamates.
Generic Name
Riluzole
Drug Description
RILUTEK 50 mg film-coated tablets
Presentation
Film-coated tablet The tablets are capsule-shaped, white and engraved with “RPR 202” on one side
Indications
RILUTEK is indicated to extend life or the time to mechanical ventilation for patients with amyotrophic lateral sclerosis (ALS).Clinical trials have demonstrated that RILUTEK extends survival for patients with ALS. Survival was defined as patients who were alive, not intubated for mechanical ventilation and tracheotomy-free.There is no evidence that RILUTEK exerts a therapeutic effect on motor function, lung function, fasciculations, muscle strength and motor symptoms. RILUTEK has not been shown to be effective in the late stages of ALS.Safety and efficacy of RILUTEK has only been studied in ALS. Therefore, RILUTEK should not be used in patients with any other form of motor neurone disease.
Adult Dosage
Treatment with RILUTEK should only be initiated by specialist physicians with experience in the management of motor neurone diseases.
The recommended daily dose in adults or elderly is 100 mg (50 mg every 12 hours).
No significant increased benefit can be expected from higher daily doses.
Special populations
Children
